The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition

The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition

Two hypotheses have been proposed recently that offer different views on the role of airway surface liquid (ASL) in lung defense. The "compositional" hypothesis predicts that ASL [NaCl] is kept low (

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Veröffentlicht in:The Journal of general physiology 2001-08, Vol.118 (2), p.223-236
Hauptverfasser: Tarran, R, Grubb, B R, Gatzy, J T, Davis, C W, Boucher, R C
Format: Artikel
Sprache:eng
Schlagworte:
Biological Transport, Active - physiology
Body Fluids - chemistry
Body Fluids - metabolism
Cells, Cultured
Cilia - physiology
Cystic fibrosis
Homeostasis - physiology
Humans
Ions
Lung - metabolism
Lung - physiology
Lungs
Mucus - metabolism
Original
Osmolar Concentration
Salt
Surface Tension
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Beschreibung
Zusammenfassung:Two hypotheses have been proposed recently that offer different views on the role of airway surface liquid (ASL) in lung defense. The "compositional" hypothesis predicts that ASL [NaCl] is kept low (
ISSN:0022-1295
1540-7748
DOI:10.1085/jgp.118.2.223