Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands
3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.
Gespeichert in:
| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2006-01 (45), p.4685-4687 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 4687 |
|---|---|
| container_issue | 45 |
| container_start_page | 4685 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | |
| creator | Gonçalves, Diana P N Rodriguez, Raphaël Balasubramanian, Shankar Sanders, Jeremy K M |
| description | 3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones. |
| doi_str_mv | 10.1039/b611731g |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2220048</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68151639</sourcerecordid><originalsourceid>FETCH-LOGICAL-c403t-1ee8ba5d360a78a1d58e6e8609250e632b2441ed795037c423148dffbdd09e273</originalsourceid><addsrcrecordid>eNp9kU1r3DAQhkVpyWehv6D4VHJxotGX5UuhDe0mEOglhdxU2RrvqsiyI9lNt7--XrIkzaVzma-HlxleQt4BPQfK64tGAVQc1q_IEXAlSin03etdLeuy4kIekuOcf9IlQOoDcggV0JpydUR-3OKUbI_TZhvGbfLORz_345DGzTbZPz5iLktbRHwo2mBzLoauWJX3s3VpHgP-Lnx0c-vjurDRFXmyjQ8-7_rg18son5I3nQ0Z3-7zCfn-9cvt5VV58211ffnppmwF5VMJiLqx0nFFbaUtOKlRoVa0ZpKi4qxhQgC6qpaUV61gHIR2Xdc4R2tkFT8hHx91x7np0bUYl7-CGZPvbdqawXrzchP9xqyHX4YxRqnQi8CHvUAa7mfMk-l9bjEEG3GYs1EaJCheL-DZf0HGqWRC1SCf0TYNOSfsnu4BanbOmc-Pzq0W9P2_9z-De6v4Xw-llaw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2305246915</pqid></control><display><type>article</type><title>Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands</title><source>Royal Society of Chemistry Journals Archive (1841-2007)</source><source>MEDLINE</source><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Gonçalves, Diana P N ; Rodriguez, Raphaël ; Balasubramanian, Shankar ; Sanders, Jeremy K M</creator><creatorcontrib>Gonçalves, Diana P N ; Rodriguez, Raphaël ; Balasubramanian, Shankar ; Sanders, Jeremy K M</creatorcontrib><description>3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.</description><identifier>ISSN: 1359-7345</identifier><identifier>ISSN: 1364-548X</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/b611731g</identifier><identifier>PMID: 17109036</identifier><language>eng</language><publisher>England</publisher><subject>chemical reactions ; DNA ; DNA - chemistry ; G-Quadruplexes ; humans ; Ligands ; Methylation ; molecular chaperones ; Molecular Structure ; Porphyrins - chemistry ; Pyridines - chemistry ; Spectrum Analysis ; telomeres</subject><ispartof>Chemical communications (Cambridge, England), 2006-01 (45), p.4685-4687</ispartof><rights>The Royal Society of Chemistry 2006 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-1ee8ba5d360a78a1d58e6e8609250e632b2441ed795037c423148dffbdd09e273</citedby><cites>FETCH-LOGICAL-c403t-1ee8ba5d360a78a1d58e6e8609250e632b2441ed795037c423148dffbdd09e273</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,2818,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17109036$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gonçalves, Diana P N</creatorcontrib><creatorcontrib>Rodriguez, Raphaël</creatorcontrib><creatorcontrib>Balasubramanian, Shankar</creatorcontrib><creatorcontrib>Sanders, Jeremy K M</creatorcontrib><title>Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.</description><subject>chemical reactions</subject><subject>DNA</subject><subject>DNA - chemistry</subject><subject>G-Quadruplexes</subject><subject>humans</subject><subject>Ligands</subject><subject>Methylation</subject><subject>molecular chaperones</subject><subject>Molecular Structure</subject><subject>Porphyrins - chemistry</subject><subject>Pyridines - chemistry</subject><subject>Spectrum Analysis</subject><subject>telomeres</subject><issn>1359-7345</issn><issn>1364-548X</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1r3DAQhkVpyWehv6D4VHJxotGX5UuhDe0mEOglhdxU2RrvqsiyI9lNt7--XrIkzaVzma-HlxleQt4BPQfK64tGAVQc1q_IEXAlSin03etdLeuy4kIekuOcf9IlQOoDcggV0JpydUR-3OKUbI_TZhvGbfLORz_345DGzTbZPz5iLktbRHwo2mBzLoauWJX3s3VpHgP-Lnx0c-vjurDRFXmyjQ8-7_rg18son5I3nQ0Z3-7zCfn-9cvt5VV58211ffnppmwF5VMJiLqx0nFFbaUtOKlRoVa0ZpKi4qxhQgC6qpaUV61gHIR2Xdc4R2tkFT8hHx91x7np0bUYl7-CGZPvbdqawXrzchP9xqyHX4YxRqnQi8CHvUAa7mfMk-l9bjEEG3GYs1EaJCheL-DZf0HGqWRC1SCf0TYNOSfsnu4BanbOmc-Pzq0W9P2_9z-De6v4Xw-llaw</recordid><startdate>20060101</startdate><enddate>20060101</enddate><creator>Gonçalves, Diana P N</creator><creator>Rodriguez, Raphaël</creator><creator>Balasubramanian, Shankar</creator><creator>Sanders, Jeremy K M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7S9</scope><scope>L.6</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20060101</creationdate><title>Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands</title><author>Gonçalves, Diana P N ; Rodriguez, Raphaël ; Balasubramanian, Shankar ; Sanders, Jeremy K M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-1ee8ba5d360a78a1d58e6e8609250e632b2441ed795037c423148dffbdd09e273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>chemical reactions</topic><topic>DNA</topic><topic>DNA - chemistry</topic><topic>G-Quadruplexes</topic><topic>humans</topic><topic>Ligands</topic><topic>Methylation</topic><topic>molecular chaperones</topic><topic>Molecular Structure</topic><topic>Porphyrins - chemistry</topic><topic>Pyridines - chemistry</topic><topic>Spectrum Analysis</topic><topic>telomeres</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gonçalves, Diana P N</creatorcontrib><creatorcontrib>Rodriguez, Raphaël</creatorcontrib><creatorcontrib>Balasubramanian, Shankar</creatorcontrib><creatorcontrib>Sanders, Jeremy K M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gonçalves, Diana P N</au><au>Rodriguez, Raphaël</au><au>Balasubramanian, Shankar</au><au>Sanders, Jeremy K M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2006-01-01</date><risdate>2006</risdate><issue>45</issue><spage>4685</spage><epage>4687</epage><pages>4685-4687</pages><issn>1359-7345</issn><issn>1364-548X</issn><eissn>1364-548X</eissn><abstract>3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.</abstract><cop>England</cop><pmid>17109036</pmid><doi>10.1039/b611731g</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2006-01 (45), p.4685-4687 |
| issn | 1359-7345 1364-548X 1364-548X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2220048 |
| source | Royal Society of Chemistry Journals Archive (1841-2007); MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | chemical reactions DNA DNA - chemistry G-Quadruplexes humans Ligands Methylation molecular chaperones Molecular Structure Porphyrins - chemistry Pyridines - chemistry Spectrum Analysis telomeres |
| title | Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T20%3A30%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Tetramethylpyridiniumporphyrazines--a%20new%20class%20of%20G-quadruplex%20inducing%20and%20stabilising%20ligands&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Gon%C3%A7alves,%20Diana%20P%20N&rft.date=2006-01-01&rft.issue=45&rft.spage=4685&rft.epage=4687&rft.pages=4685-4687&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/b611731g&rft_dat=%3Cproquest_pubme%3E68151639%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2305246915&rft_id=info:pmid/17109036&rfr_iscdi=true |