Harry Goldblatt and the discovery of renin

Harry Goldblatt and the discovery of renin

In 1934, pathologist Harry Goldblatt established the first animal model of hypertension. This model provided researchers with the tools to delineate the renin-angiotensin system of blood pressure control and, eventually, to design enzyme inhibitors for the treatment of chronic hypertension.

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Bibliographische Detailangaben
Veröffentlicht in:The Journal of experimental medicine 2005-05, Vol.201 (9), p.1351-1351
1. Verfasser: Van Epps, Heather L
Format: Artikel
Sprache:eng
Schlagworte:
From the Archive
Goldblatt
History, 20th Century
Hypertension - pathology
Kidney - metabolism
Kidney - pathology
Models, Animal
Renin - metabolism
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Beschreibung
Zusammenfassung:In 1934, pathologist Harry Goldblatt established the first animal model of hypertension. This model provided researchers with the tools to delineate the renin-angiotensin system of blood pressure control and, eventually, to design enzyme inhibitors for the treatment of chronic hypertension.
ISSN:0022-1007
1540-9538
1892-1007
DOI:10.1084/jem.2019fta