Interpretation of tracer washout curves from a population of muscle fibers

Consideration is given to the role of a population of muscle fibers of distributed diameters in the observed washout of a tracer, with particular reference to radioisotopic K and muscle fibers. It is concluded that if washout of tracer from a single fiber is described as first order, then washout of...

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Veröffentlicht in:The Journal of general physiology 1966-01, Vol.49 (3), p.423-431
1. Verfasser: Zierler, K L
Format: Artikel
Sprache:eng
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Zusammenfassung:Consideration is given to the role of a population of muscle fibers of distributed diameters in the observed washout of a tracer, with particular reference to radioisotopic K and muscle fibers. It is concluded that if washout of tracer from a single fiber is described as first order, then washout of tracer from a population of fibers is apt to appear as first order.
ISSN:0022-1295
1540-7748
DOI:10.1085/jgp.49.3.423