Signaling to Actin Dynamics

The actin cytoskeleton of a eukaryotic cell is central to locomotion, contractility, phagocytosis, shape changes, cytokinesis, and maintenance of polarity. Machesky and Insall discuss how cells control actin polymerization to produce the force for motility and shape changes.

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Bibliographische Detailangaben
Veröffentlicht in:	The Journal of cell biology 1999-07, Vol.146 (2), p.267-272
Hauptverfasser:	Machesky, Laura M., Insall, Robert H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Depolymerizing Factors Actins Actins - metabolism Animals Biochemistry cdc42 GTP-Binding Protein Cell Adhesion Molecules - metabolism Cell Cycle Proteins - metabolism Cells Cellular biology Destrin Gelsolin - metabolism GTP-Binding Proteins - metabolism Humans Lymphocytes Microfilament Proteins - metabolism Microfilaments Mini-Review Models, Biological Monomers Muscular system Nucleation Phosphoproteins - metabolism Physiological regulation Polymerization Profilins Proteins Proteins - metabolism Receptors Signal Transduction Wiskott-Aldrich Syndrome Protein
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Beschreibung
Zusammenfassung:	The actin cytoskeleton of a eukaryotic cell is central to locomotion, contractility, phagocytosis, shape changes, cytokinesis, and maintenance of polarity. Machesky and Insall discuss how cells control actin polymerization to produce the force for motility and shape changes.
ISSN:	0021-9525 1540-8140
DOI:	10.1083/jcb.146.2.267