H-2-linked genetic control of immune responsiveness to ovalbumin and ovomucoid
Immune responsiveness of inbred mice to low doses of ovalbumin or ovomucoid is under control of single dominant genes closely linked to alleles of the H-2 locus. High responsiveness to ovomucoid is linked with the H-2(a) and H-2(k) alleles, and to ovalbumin with the H-2(b), H-2(d), and H-2(q) allele...
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| Veröffentlicht in: | The Journal of experimental medicine 1971-11, Vol.134 (5), p.1335-1348 |
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| container_end_page | 1348 |
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| container_issue | 5 |
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| container_title | The Journal of experimental medicine |
| container_volume | 134 |
| creator | Vaz, N M Phillips-Quagliata, J M Levine, B B Vaz, E M |
| description | Immune responsiveness of inbred mice to low doses of ovalbumin or ovomucoid is under control of single dominant genes closely linked to alleles of the H-2 locus. High responsiveness to ovomucoid is linked with the H-2(a) and H-2(k) alleles, and to ovalbumin with the H-2(b), H-2(d), and H-2(q) alleles. |
| doi_str_mv | 10.1084/jem.134.5.1335 |
| format | Article |
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High responsiveness to ovomucoid is linked with the H-2(a) and H-2(k) alleles, and to ovalbumin with the H-2(b), H-2(d), and H-2(q) alleles.</description><identifier>ISSN: 0022-1007</identifier><identifier>EISSN: 1540-9538</identifier><identifier>DOI: 10.1084/jem.134.5.1335</identifier><identifier>PMID: 5112206</identifier><language>eng</language><publisher>United States: The Rockefeller University Press</publisher><subject>Alleles ; Animals ; Antibody Formation ; Female ; Genes, Dominant ; Histocompatibility ; Immunogenetics ; Inbreeding ; Isoantigens ; Mice ; Mucoproteins - administration & dosage ; Mucoproteins - pharmacology ; Ovalbumin - administration & dosage ; Ovalbumin - pharmacology ; Passive Cutaneous Anaphylaxis</subject><ispartof>The Journal of experimental medicine, 1971-11, Vol.134 (5), p.1335-1348</ispartof><rights>Copyright © 1971 by The Rockefeller University Press</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-cb6360abc6d6aff190a38e326f13e67cdc3c52b10fdb17f4479062486766cbd03</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5112206$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vaz, N M</creatorcontrib><creatorcontrib>Phillips-Quagliata, J M</creatorcontrib><creatorcontrib>Levine, B B</creatorcontrib><creatorcontrib>Vaz, E M</creatorcontrib><title>H-2-linked genetic control of immune responsiveness to ovalbumin and ovomucoid</title><title>The Journal of experimental medicine</title><addtitle>J Exp Med</addtitle><description>Immune responsiveness of inbred mice to low doses of ovalbumin or ovomucoid is under control of single dominant genes closely linked to alleles of the H-2 locus. High responsiveness to ovomucoid is linked with the H-2(a) and H-2(k) alleles, and to ovalbumin with the H-2(b), H-2(d), and H-2(q) alleles.</description><subject>Alleles</subject><subject>Animals</subject><subject>Antibody Formation</subject><subject>Female</subject><subject>Genes, Dominant</subject><subject>Histocompatibility</subject><subject>Immunogenetics</subject><subject>Inbreeding</subject><subject>Isoantigens</subject><subject>Mice</subject><subject>Mucoproteins - administration & dosage</subject><subject>Mucoproteins - pharmacology</subject><subject>Ovalbumin - administration & dosage</subject><subject>Ovalbumin - pharmacology</subject><subject>Passive Cutaneous Anaphylaxis</subject><issn>0022-1007</issn><issn>1540-9538</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkctLxDAQxoMouj6u3oSevHWdyavtRZDFF4he9BzSNNWsbbI27YL_vVlcFr3MMMxvvhnmI-QcYY5Q8qul7efI-FykyMQemaHgkFeClftkBkBpjgDFETmOcQmAnAt5SA4FIqUgZ-T5Iad55_ynbbJ36-3oTGaCH4fQZaHNXN9P3maDjavgo1snIsZsDFlY666eeucz7ZtUhX4ywTWn5KDVXbRn23xC3u5uXxcP-dPL_ePi5ik3XOCYm1oyCbo2spG6bbECzUrLqGyRWVmYxjAjaI3QNjUWLedFBZLyUhZSmroBdkKuf3VXU93bxth0se7UanC9Hr5V0E7973j3od7DWlFkFaBIApdbgSF8TTaOqnfR2K7T3oYpqhKRSVbxBM5_QTOEGAfb7pYgqI0DKjmgkgNKqI0DaeDi72k7fPty9gM2v4Oh</recordid><startdate>19711101</startdate><enddate>19711101</enddate><creator>Vaz, N M</creator><creator>Phillips-Quagliata, J M</creator><creator>Levine, B B</creator><creator>Vaz, E M</creator><general>The Rockefeller University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19711101</creationdate><title>H-2-linked genetic control of immune responsiveness to ovalbumin and ovomucoid</title><author>Vaz, N M ; Phillips-Quagliata, J M ; Levine, B B ; Vaz, E M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-cb6360abc6d6aff190a38e326f13e67cdc3c52b10fdb17f4479062486766cbd03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Alleles</topic><topic>Animals</topic><topic>Antibody Formation</topic><topic>Female</topic><topic>Genes, Dominant</topic><topic>Histocompatibility</topic><topic>Immunogenetics</topic><topic>Inbreeding</topic><topic>Isoantigens</topic><topic>Mice</topic><topic>Mucoproteins - administration & dosage</topic><topic>Mucoproteins - pharmacology</topic><topic>Ovalbumin - administration & dosage</topic><topic>Ovalbumin - pharmacology</topic><topic>Passive Cutaneous Anaphylaxis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vaz, N M</creatorcontrib><creatorcontrib>Phillips-Quagliata, J M</creatorcontrib><creatorcontrib>Levine, B B</creatorcontrib><creatorcontrib>Vaz, E M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Journal of experimental medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vaz, N M</au><au>Phillips-Quagliata, J M</au><au>Levine, B B</au><au>Vaz, E M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>H-2-linked genetic control of immune responsiveness to ovalbumin and ovomucoid</atitle><jtitle>The Journal of experimental medicine</jtitle><addtitle>J Exp Med</addtitle><date>1971-11-01</date><risdate>1971</risdate><volume>134</volume><issue>5</issue><spage>1335</spage><epage>1348</epage><pages>1335-1348</pages><issn>0022-1007</issn><eissn>1540-9538</eissn><abstract>Immune responsiveness of inbred mice to low doses of ovalbumin or ovomucoid is under control of single dominant genes closely linked to alleles of the H-2 locus. 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| identifier | ISSN: 0022-1007 |
| ispartof | The Journal of experimental medicine, 1971-11, Vol.134 (5), p.1335-1348 |
| issn | 0022-1007 1540-9538 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Alleles Animals Antibody Formation Female Genes, Dominant Histocompatibility Immunogenetics Inbreeding Isoantigens Mice Mucoproteins - administration & dosage Mucoproteins - pharmacology Ovalbumin - administration & dosage Ovalbumin - pharmacology Passive Cutaneous Anaphylaxis |
| title | H-2-linked genetic control of immune responsiveness to ovalbumin and ovomucoid |
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