Synthesis of irreversibly binding bicalutamide analogs for imaging studies

Synthesis of irreversibly binding bicalutamide analogs for imaging studies

[Display omitted] A new synthetic methodology for preparing radioactive androgen receptor binding compounds in order to determine receptor–ligands interactions has been developed.

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Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron letters 2005-07, Vol.46 (28), p.4821-4823
Hauptverfasser: Nair, Vipin A., Mustafa, Suni M., Mohler, Michael L., Yang, Jun, Kirkovsky, Leonid I., Dalton, James T., Miller, Duane D.
Format: Artikel
Sprache:eng
Schlagworte:
Androgen
Bicalutamide
Iodine
Radioactive
Receptor
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Beschreibung
Zusammenfassung:[Display omitted] A new synthetic methodology for preparing radioactive androgen receptor binding compounds in order to determine receptor–ligands interactions has been developed.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2005.04.143