A modified haemagglutination inhibition test for rubella antibodies, using standardized, freeze-dried reagents. Report of a comparative multi-centre trial

A modified haemagglutination inhibition test for rubella antibodies, using standardized freeze-dried reagents, was developed and compared with haemagglutination inhibition tests using fresh erythrocytes. This comparison was made in collaboration with six European laboratories. A total of 4205 serum...

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Veröffentlicht in:	The Journal of hygiene 1976-08, Vol.77 (1), p.31-42
Hauptverfasser:	van Weemen, Bauke K., Kacaki, Jovan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Viral - analysis Chemical suspensions Erythrocytes Fluorescent Antibody Technique Fluorescent antibody techniques Freeze Drying Hemagglutination Inhibition Tests Humans Indicators and Reagents International Cooperation Public health Reagents Rubella Rubella virus - immunology Screening tests Standardization Virology
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Beschreibung
Zusammenfassung:	A modified haemagglutination inhibition test for rubella antibodies, using standardized freeze-dried reagents, was developed and compared with haemagglutination inhibition tests using fresh erythrocytes. This comparison was made in collaboration with six European laboratories. A total of 4205 serum samples were tested. The results show that: (1) Sensitivity and reliability of the modified test are good; (2) the modified test can be performed in glass tubes as well as in polystyrene microtitration plates.
ISSN:	0022-1724 2396-8184
DOI:	10.1017/S0022172400055480