Cognitive outcome in adults after bacterial meningitis

Objective:To evaluate cognitive outcome in adult survivors of bacterial meningitis.Methods:Data from three prospective multicentre studies were pooled and reanalysed, involving 155 adults surviving bacterial meningitis (79 after pneumococcal and 76 after meningococcal meningitis) and 72 healthy cont...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2007-10, Vol.78 (10), p.1092-1096
Hauptverfasser:	Hoogman, Martine, van de Beek, Diederik, Weisfelt, Martijn, de Gans, Jan, Schmand, Ben
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Age of Onset Analysis of Variance Bacteria Bacterial diseases Bacterial diseases of the nervous system. Bacterial myositis Biological and medical sciences Causality Cognition Disorders - classification Cognition Disorders - epidemiology Cognitive ability Comorbidity Cranial Nerve Diseases - epidemiology Dexamethasone - therapeutic use Female Glasgow Coma Scale Human bacterial diseases Humans Infectious diseases Intelligence tests Male Medical sciences Memory Meningitis Meningitis, Meningococcal - drug therapy Meningitis, Meningococcal - epidemiology Meningitis, Pneumococcal - drug therapy Meningitis, Pneumococcal - epidemiology Middle Aged Neisseria meningitidis Neurology Neuropsychological Tests Odds Ratio Sex Distribution Staphylococcal infections, streptococcal infections, pneumococcal infections Streptococcus infections Streptococcus pneumoniae Studies
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Zusammenfassung:	Objective:To evaluate cognitive outcome in adult survivors of bacterial meningitis.Methods:Data from three prospective multicentre studies were pooled and reanalysed, involving 155 adults surviving bacterial meningitis (79 after pneumococcal and 76 after meningococcal meningitis) and 72 healthy controls.Results:Cognitive impairment was found in 32% of patients and this proportion was similar for survivors of pneumococcal and meningococcal meningitis. Survivors of pneumococcal meningitis performed worse on memory tasks (p
ISSN:	0022-3050 1468-330X 1468-330X
DOI:	10.1136/jnnp.2006.110023