Dura mater-associated Creutzfeldt–Jakob disease: experience from surveillance in the UK

Between 1970 and 2003, seven cases of human dura mater-associated Creutzfeldt–Jakob disease (CJD) were identified in the UK. Furthermore, we identified a case of CJD in a porcine dura graft recipient. The mean incubation period of the human dura mater cases was 93 (range 45–177) months. The clinico-...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2006-07, Vol.77 (7), p.880-882
Hauptverfasser:	Heath, C A, Barker, R A, Esmonde, T F G, Harvey, P, Roberts, R, Trend, P, Head, M W, Smith, C, Bell, J E, Ironside, J W, Will, R G, Knight, R S G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Biological and medical sciences Bovine spongiform encephalopathy Creutzfeldt-Jakob disease Creutzfeldt-Jakob Syndrome - epidemiology Creutzfeldt-Jakob Syndrome - pathology Creutzfeldt-Jakob Syndrome - transmission Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dura Mater - pathology Dura Mater - transplantation Electroencephalography Female Growth hormones Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Iatrogenic Disease Male Medical sciences Mutation Nervous system (semeiology, syndromes) Neurology Population Surveillance Short Report Surgery Surveillance Swine Time Factors Transplantation, Heterologous - adverse effects United Kingdom - epidemiology
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Beschreibung
Zusammenfassung:	Between 1970 and 2003, seven cases of human dura mater-associated Creutzfeldt–Jakob disease (CJD) were identified in the UK. Furthermore, we identified a case of CJD in a porcine dura graft recipient. The mean incubation period of the human dura mater cases was 93 (range 45–177) months. The clinico-pathological features of the cases are described and compared with cases previously reported in the world literature.
ISSN:	0022-3050 1468-330X
DOI:	10.1136/jnnp.2005.073395