Clinical and serological study of myasthenia gravis in HuBei Province, China

Background: Ocular and childhood myasthenia gravis (MG) cases seem relatively more common in Oriental than in Caucasian populations, but there have been no comprehensive serological studies on patients from mainland China. Methods: 391 unselected patients with MG attending Tongji Hospital in WuHan (...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2007-04, Vol.78 (4), p.386-390
Hauptverfasser:	Zhang, Xiaofan, Yang, Mingshan, Xu, Jinzhi, Zhang, Min, Lang, Bethan, Wang, Wei, Vincent, Angela
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine receptor AChR Adolescent Adult Adults Age of Onset Aged Autoantibodies - blood Biological and medical sciences Case-Control Studies Child Child, Preschool China - ethnology Disease Diseases of striated muscles. Neuromuscular diseases Eye Diseases - etiology Female Females Histology Humans Immunoglobulins Infant Infant, Newborn Laboratories Magnetic Resonance Imaging Male Medical sciences MGFA Middle Aged Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis muscle-specific kinase MuSK myasthenia gravis Myasthenia Gravis - complications Myasthenia Gravis - ethnology Myasthenia Gravis - immunology Myasthenia Gravis - pathology Myasthenia Gravis Foundation of America Neurology Pathology Patients Receptors, Cholinergic - immunology seronegative myasthenia gravis Sex Ratio SNMG Studies Thymoma - etiology Thymus Neoplasms - etiology VGCC voltage-gated calcium channel White people
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Zusammenfassung:	Background: Ocular and childhood myasthenia gravis (MG) cases seem relatively more common in Oriental than in Caucasian populations, but there have been no comprehensive serological studies on patients from mainland China. Methods: 391 unselected patients with MG attending Tongji Hospital in WuHan (the largest hospital in the province of HuBei, China) were studied during a 15-month period; most had already received treatment for their condition. Results: The male to female ratio was 0.8. 50% of the patients were children (
ISSN:	0022-3050 1468-330X
DOI:	10.1136/jnnp.2006.100545