Thrombolysis for acute stroke with special emphasis on the very old: experience from a single Dutch centre

The aim of this study was to describe the clinical experience in 184 consecutive stroke patients first-ever treated with recombinant tissue plasminogen activator (rt-PA) at a single Dutch centre, with special emphasis on results among the very old. Outcome parameters were the modified Rankin scale (...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2006-03, Vol.77 (3), p.375-377
Hauptverfasser:	van Oostenbrugge, R J, Hupperts, R M M, Lodder, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of Daily Living - classification acute stroke Age Age Factors Aged, 80 and over Blood pressure Brain Damage, Chronic - diagnosis Cardiovascular disease cerebral infarction Female Humans Infarction, Middle Cerebral Artery - diagnosis Infarction, Middle Cerebral Artery - drug therapy Intracranial Hemorrhages - chemically induced Ischemia Male MCA Medical imaging middle cerebral artery modified Rankin scale mRs National Institutes of Health Stroke Scale NIHSS randomised controlled trial RCT recombinant tissue plasminogen activator Risk Assessment rt-PA Short Report SICH Stroke symptomatic intracranial haemorrhage thrombolysis Thrombolytic Therapy - adverse effects Tissue Plasminogen Activator - adverse effects Tissue Plasminogen Activator - therapeutic use Treatment Outcome Veins & arteries very old
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The aim of this study was to describe the clinical experience in 184 consecutive stroke patients first-ever treated with recombinant tissue plasminogen activator (rt-PA) at a single Dutch centre, with special emphasis on results among the very old. Outcome parameters were the modified Rankin scale (mRs) at 3 months and symptomatic intracranial haemorrhage (SICH). Outcome was related to age. A total of 184 patients were treated of whom 45 were 80 years of age or older (24%). Sixty two (45%) of 139 patients
ISSN:	0022-3050 1468-330X
DOI:	10.1136/jnnp.2005.070292