Susac’s syndrome: effective combination of immunosuppression and antiplatelet treatment

From the presented case, we conclude that (1) the triad of encephalopathy, branch retinal artery occlusions and sudden hearing loss in young women strongly suggests Susac's syndrome; (2) snowball-shaped lesions in the corpus callosum appear highly specific for the clinical diagnosis of Susac's syndrome; and (3) the use of high-dose glucocorticoids in the acute phase of the disease and prophylactic treatment with aspirin and nimodipine seem to be beneficial for these patients, but has to be evaluated prospectively in larger studies.