Acute transverse myelitis at the conus medullaris level after rabies vaccination in a patient with Behçet's disease

A 25-year-old man with Behçet's disease was admitted because of weakness of the lower limbs and difficulty in urination. He had received a rabies vaccination 2 months previous because he had been bitten by a dog. Clinical and laboratory findings supported acute transverse myelitis. A hyperinten...

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Veröffentlicht in:The journal of spinal cord medicine 2007, Vol.30 (3), p.294-296
Hauptverfasser: Bir, Levent Sinan, Eşmeli, Fatma Ozdemir, Cenikli, Utku, Erdoğan, Cağdaş, Değirmenci, Eylem
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Sprache:eng
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Zusammenfassung:A 25-year-old man with Behçet's disease was admitted because of weakness of the lower limbs and difficulty in urination. He had received a rabies vaccination 2 months previous because he had been bitten by a dog. Clinical and laboratory findings supported acute transverse myelitis. A hyperintense lesion and expansion at the level of conus medullaris was detected on spinal magnetic resonance imaging. Although neurologic involvement is one of the main causes of mortality and morbidity in Behçet's disease, the factors that aggravate the involvement of the nervous system are still unclear. Vaccination may have been the factor that had activated autoimmune mechanisms in this case. To our knowledge, involvement of the conus medullaris in Behçet's disease after rabies vaccination has not been reported.
ISSN:1079-0268
2045-7723
DOI:10.1080/10790268.2007.11753940