Tests of experimental tissue adhesive sealants: analysis of strength effects in relation to tissue adhesive sealant standards

Tests of experimental tissue adhesive sealants: analysis of strength effects in relation to tissue adhesive sealant standards

The sealing efficiencies (SE% = surfaces sealed/surfaces tested) of 2 experimental tissue adhesive sealants (TASs), L.C. TAS and glutaraldehyde TAS (GA TAS), were determined by applications in 12 mixed-breed pigs (weight range, 40-60 kg) that had been anticoagulated with heparin and divided into gro...

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Veröffentlicht in:Texas Heart Institute journal 2007, Vol.34 (3), p.313-317
Hauptverfasser: Browdie, David A, Cox, David
Format: Artikel
Sprache:eng
Schlagworte:
Adhesiveness
Animals
Glutaral
Laboratory Investigation
Materials Testing
Swine
Tissue Adhesives - standards
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Zusammenfassung:The sealing efficiencies (SE% = surfaces sealed/surfaces tested) of 2 experimental tissue adhesive sealants (TASs), L.C. TAS and glutaraldehyde TAS (GA TAS), were determined by applications in 12 mixed-breed pigs (weight range, 40-60 kg) that had been anticoagulated with heparin and divided into groups of 6: Group I, L.C. TAS; and Group II, GA TAS. Leaking tissue surfaces used were 5-mm aortic punch holes and lacerated splenic, hepatic, and lung surfaces (2 of each, in each pig). First-application SEs were as follows: for aortic punch holes, 91% in Group I and 16.6% in Group II (P
ISSN:0730-2347