Absence of HPV 16 and 18 DNA in breast cancer

The finding that human papillomavirus (HPV) genes can immortalise breast epithelial cells has led to suggestions that HPV could be involved in the pathogenesis of breast cancer. Using the polymerase chain reaction (PCR) we have been unable to demonstrate the presence of HPV DNA in a series of 80 bre...

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Veröffentlicht in:	British journal of cancer 1992-06, Vol.65 (6), p.891-894
Hauptverfasser:	Wrede, D, Luqmani, YA, Coombes, RC, Vousden, KH
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Base Sequence Biological and medical sciences Biomedical and Life Sciences Biomedicine Breast Neoplasms - microbiology Cancer Research DNA, Viral - analysis Drug Resistance Epidemiology experimental-oncology Female Genital system. Mammary gland Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Menopause Middle Aged Molecular Medicine Molecular Sequence Data Oligodeoxyribonucleotides - chemistry Oncology Papillomaviridae - chemistry Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Polymerase Chain Reaction
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Beschreibung
Zusammenfassung:	The finding that human papillomavirus (HPV) genes can immortalise breast epithelial cells has led to suggestions that HPV could be involved in the pathogenesis of breast cancer. Using the polymerase chain reaction (PCR) we have been unable to demonstrate the presence of HPV DNA in a series of 80 breast carcinomas.
ISSN:	0007-0920 1532-1827
DOI:	10.1038/bjc.1992.186