Abducens palsy and Sjögren’s syndrome induced by pegylated interferon therapy

The enhancement of the abducens nerve is seen in disseminated tumour, inflammation, trauma, venous congestion or autoimmune disease, but less likely in diabetic microinfarcts. 6 We assume that the IFN-activated immune system induced an acute inflammatory process in the abducens nerve, which appeared...

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Veröffentlicht in:British journal of ophthalmology 2007-06, Vol.91 (6), p.843-844
Hauptverfasser: Oishi, Akio, Miyamoto, Kazuaki, Kashii, Satoshi, Yoshimura, Nagahisa
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container_issue 6
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container_title British journal of ophthalmology
container_volume 91
creator Oishi, Akio
Miyamoto, Kazuaki
Kashii, Satoshi
Yoshimura, Nagahisa
description The enhancement of the abducens nerve is seen in disseminated tumour, inflammation, trauma, venous congestion or autoimmune disease, but less likely in diabetic microinfarcts. 6 We assume that the IFN-activated immune system induced an acute inflammatory process in the abducens nerve, which appeared as the enhancement, and led to ensuing development of SS. [...]IFNs have complex immunomodulating effects and frequently induce or exacerbate autoimmune disease. 7, 8 The symptom resolved spontaneously as abducens palsy usually does.
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subjects Abducens Nerve Diseases - chemically induced
Aged
Antineoplastic Agents - adverse effects
Autoimmune diseases
Disease
Humans
Hypertension
Interferon-alpha - adverse effects
Letters
Male
Paralysis - chemically induced
Polyethylene Glycols - adverse effects
Recombinant Proteins
Sjogren's Syndrome - chemically induced
title Abducens palsy and Sjögren’s syndrome induced by pegylated interferon therapy
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