Abducens palsy and Sjögren’s syndrome induced by pegylated interferon therapy
The enhancement of the abducens nerve is seen in disseminated tumour, inflammation, trauma, venous congestion or autoimmune disease, but less likely in diabetic microinfarcts. 6 We assume that the IFN-activated immune system induced an acute inflammatory process in the abducens nerve, which appeared...
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Veröffentlicht in: | British journal of ophthalmology 2007-06, Vol.91 (6), p.843-844 |
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creator | Oishi, Akio Miyamoto, Kazuaki Kashii, Satoshi Yoshimura, Nagahisa |
description | The enhancement of the abducens nerve is seen in disseminated tumour, inflammation, trauma, venous congestion or autoimmune disease, but less likely in diabetic microinfarcts. 6 We assume that the IFN-activated immune system induced an acute inflammatory process in the abducens nerve, which appeared as the enhancement, and led to ensuing development of SS. [...]IFNs have complex immunomodulating effects and frequently induce or exacerbate autoimmune disease. 7, 8 The symptom resolved spontaneously as abducens palsy usually does. |
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[...]IFNs have complex immunomodulating effects and frequently induce or exacerbate autoimmune disease. 7, 8 The symptom resolved spontaneously as abducens palsy usually does.</description><identifier>ISSN: 0007-1161</identifier><identifier>EISSN: 1468-2079</identifier><identifier>DOI: 10.1136/bjo.2006.110494</identifier><identifier>PMID: 17510485</identifier><identifier>CODEN: BJOPAL</identifier><language>eng</language><publisher>BMA House, Tavistock Square, London, WC1H 9JR: BMJ Publishing Group Ltd</publisher><subject>Abducens Nerve Diseases - chemically induced ; Aged ; Antineoplastic Agents - adverse effects ; Autoimmune diseases ; Disease ; Humans ; Hypertension ; Interferon-alpha - adverse effects ; Letters ; Male ; Paralysis - chemically induced ; Polyethylene Glycols - adverse effects ; Recombinant Proteins ; Sjogren's Syndrome - chemically induced</subject><ispartof>British journal of ophthalmology, 2007-06, Vol.91 (6), p.843-844</ispartof><rights>Copyright 2007 British Journal of Ophthalmology</rights><rights>Copyright: 2007 Copyright 2007 British Journal of Ophthalmology</rights><rights>Copyright © 2007 BMJ Publishing Group</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b461t-ab0339762932d46498996697f5fd9fbbf6c86af23a5e06498c37de1894de18303</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://bjo.bmj.com/content/91/6/843.2.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://bjo.bmj.com/content/91/6/843.2.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,230,314,724,777,781,882,3183,23552,27905,27906,53772,53774,77349,77380</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17510485$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Oishi, Akio</creatorcontrib><creatorcontrib>Miyamoto, Kazuaki</creatorcontrib><creatorcontrib>Kashii, Satoshi</creatorcontrib><creatorcontrib>Yoshimura, Nagahisa</creatorcontrib><title>Abducens palsy and Sjögren’s syndrome induced by pegylated interferon therapy</title><title>British journal of ophthalmology</title><addtitle>Br J Ophthalmol</addtitle><description>The enhancement of the abducens nerve is seen in disseminated tumour, inflammation, trauma, venous congestion or autoimmune disease, but less likely in diabetic microinfarcts. 6 We assume that the IFN-activated immune system induced an acute inflammatory process in the abducens nerve, which appeared as the enhancement, and led to ensuing development of SS. [...]IFNs have complex immunomodulating effects and frequently induce or exacerbate autoimmune disease. 7, 8 The symptom resolved spontaneously as abducens palsy usually does.</description><subject>Abducens Nerve Diseases - chemically induced</subject><subject>Aged</subject><subject>Antineoplastic Agents - adverse effects</subject><subject>Autoimmune diseases</subject><subject>Disease</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Interferon-alpha - adverse effects</subject><subject>Letters</subject><subject>Male</subject><subject>Paralysis - chemically induced</subject><subject>Polyethylene Glycols - adverse effects</subject><subject>Recombinant Proteins</subject><subject>Sjogren's Syndrome - chemically induced</subject><issn>0007-1161</issn><issn>1468-2079</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFkctKxDAUhoMoOl7W7qTgTqgmTZo0G0EGdZTxhhfchWSajq0zaU06Yne-hi_iC_gmPokpHbys3CQc_i__OTk_AJsI7iKE6Z4qyt0IQuorSDhZAD1EaBJGkPFF0IMQshAhilbAqnOFLyOK2DJYQSz2fBL3wOWBSmcjbVxQyYlrAmnS4Lr4eB9bbT5f31zgGpPacqqD3LRgGqgmqPS4mcjaF7mptc20LU1QP2grq2YdLGXeSW_M7zVwe3R40x-Ew4vjk_7BMFSEojqUCmLMGY04jlJCCU84p5SzLM5SnimV0VFCZRZhGWvYyiPMUo0STtoTQ7wG9jvfaqamOvVfqK2ciMrmU2kbUcpc_FVM_iDG5bNAPI79FrzB9tzAlk8z7WpRlDNr_MwCMZbwiKAk9tReR41s6ZzV2XcHBEUbgfARiDYC0UXgX2z9HuyHn-_cA2EH5K7WL9-6tI-CMsxicX7XF6dnV5AMTu_F0PM7Ha-mxb_dvwDQF6C3</recordid><startdate>200706</startdate><enddate>200706</enddate><creator>Oishi, Akio</creator><creator>Miyamoto, Kazuaki</creator><creator>Kashii, Satoshi</creator><creator>Yoshimura, Nagahisa</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>200706</creationdate><title>Abducens palsy and Sjögren’s syndrome induced by pegylated interferon therapy</title><author>Oishi, Akio ; Miyamoto, Kazuaki ; Kashii, Satoshi ; Yoshimura, Nagahisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b461t-ab0339762932d46498996697f5fd9fbbf6c86af23a5e06498c37de1894de18303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Abducens Nerve Diseases - chemically induced</topic><topic>Aged</topic><topic>Antineoplastic Agents - adverse effects</topic><topic>Autoimmune diseases</topic><topic>Disease</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Interferon-alpha - adverse effects</topic><topic>Letters</topic><topic>Male</topic><topic>Paralysis - chemically induced</topic><topic>Polyethylene Glycols - adverse effects</topic><topic>Recombinant Proteins</topic><topic>Sjogren's Syndrome - chemically induced</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Oishi, Akio</creatorcontrib><creatorcontrib>Miyamoto, Kazuaki</creatorcontrib><creatorcontrib>Kashii, Satoshi</creatorcontrib><creatorcontrib>Yoshimura, Nagahisa</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>British journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Oishi, Akio</au><au>Miyamoto, Kazuaki</au><au>Kashii, Satoshi</au><au>Yoshimura, Nagahisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Abducens palsy and Sjögren’s syndrome induced by pegylated interferon therapy</atitle><jtitle>British journal of ophthalmology</jtitle><addtitle>Br J Ophthalmol</addtitle><date>2007-06</date><risdate>2007</risdate><volume>91</volume><issue>6</issue><spage>843</spage><epage>844</epage><pages>843-844</pages><issn>0007-1161</issn><eissn>1468-2079</eissn><coden>BJOPAL</coden><abstract>The enhancement of the abducens nerve is seen in disseminated tumour, inflammation, trauma, venous congestion or autoimmune disease, but less likely in diabetic microinfarcts. 6 We assume that the IFN-activated immune system induced an acute inflammatory process in the abducens nerve, which appeared as the enhancement, and led to ensuing development of SS. [...]IFNs have complex immunomodulating effects and frequently induce or exacerbate autoimmune disease. 7, 8 The symptom resolved spontaneously as abducens palsy usually does.</abstract><cop>BMA House, Tavistock Square, London, WC1H 9JR</cop><pub>BMJ Publishing Group Ltd</pub><pmid>17510485</pmid><doi>10.1136/bjo.2006.110494</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Abducens Nerve Diseases - chemically induced Aged Antineoplastic Agents - adverse effects Autoimmune diseases Disease Humans Hypertension Interferon-alpha - adverse effects Letters Male Paralysis - chemically induced Polyethylene Glycols - adverse effects Recombinant Proteins Sjogren's Syndrome - chemically induced |
title | Abducens palsy and Sjögren’s syndrome induced by pegylated interferon therapy |
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