Reye's syndrome in a newborn infant

Reye's syndrome in a newborn infant

A case of Reye's syndrome in a newborn infant, believed to be the first recorded in the perinatal period, is reported. The clinical, biochemical and histological findings are those previously recognized in older infants. The intractable acidosis, hypoglycemia and extreme degree of lactic acidos...

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Veröffentlicht in:Canadian Medical Association journal 1973-10, Vol.109 (8), p.717-720
Hauptverfasser: Papageorgiou, A, Wiglesworth, F W, Schiff, D, Stern, L
Format: Artikel
Sprache:eng
Schlagworte:
Acidosis
Adipose Tissue
Age Factors
Brain - metabolism
Brain - pathology
Brain Diseases
Fatty Liver - genetics
Female
Hepatitis
Humans
Infant, Newborn
Infant, Newborn, Diseases
Kidney Diseases
Liver - pathology
Medical Practice
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Zusammenfassung:A case of Reye's syndrome in a newborn infant, believed to be the first recorded in the perinatal period, is reported. The clinical, biochemical and histological findings are those previously recognized in older infants. The intractable acidosis, hypoglycemia and extreme degree of lactic acidosis reflect an advanced degree of hepatic involvement, probably initiated in utero, with resultant impairment of glycogenolysis and intermediary metabolism.
ISSN:0008-4409