Clinical implications of peritoneal cytology in potentially resectable pancreatic cancer : Positive peritoneal cytology may not confer an adverse prognosis

To determine the value of peritoneal washing cytology (CY) in determining resectability of pancreatic cancer. CY has been used widely in the diagnosis and staging of several cancers. However, its predictive value in identifying potentially resectable pancreatic cancer is undetermined. Peritoneal was...

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Veröffentlicht in:Annals of surgery 2007-08, Vol.246 (2), p.254-258
Hauptverfasser: YAMADA, Suguru, TAKEDA, Shin, NAKAO, Akimasa, FUJII, Tsutomu, NOMOTO, Shuji, KANAZUMI, Naohito, SUGIMOTO, Hiroyuki, KASUYA, Hideki, KODERA, Yasuhiro, NAGASAKA, Tetsuro, MORITA, Satoshi
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Sprache:eng
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Zusammenfassung:To determine the value of peritoneal washing cytology (CY) in determining resectability of pancreatic cancer. CY has been used widely in the diagnosis and staging of several cancers. However, its predictive value in identifying potentially resectable pancreatic cancer is undetermined. Peritoneal washing samples were collected from 233 patients with pancreatic cancer between June 1991 and August 2006. A total of 157 patients had resectable and 76 had unresectable lesions. Correlations between CY status and clinicopathologic parameters with overall survival rates were analyzed. Malignant cells were identified in samples from 21 patients (13.4%) with resectable tumors and 27 patients (35.5%) with unresectable tumors. CY+ was more frequent in large tumors (> or =2 cm) than small tumors (
ISSN:0003-4932
1528-1140
DOI:10.1097/01.sla.0000261596.43439.92