Treatment of Acute Gonorrhea in Males with Synnematin B

Treatment of Acute Gonorrhea in Males with Synnematin B

There is need for a new injectable antibiotic in the treatment of gonorrhea because of the rising problem of allergy to penicillin. Synnematin B, a new antibiotic, has been demonstrated to be effective in vitro against Neisseria gonorrhoeae. A single injection of 300,000 units of synnematin B was em...

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Veröffentlicht in:Public health reports (1896) 1961-07, Vol.76 (7), p.630-632
Hauptverfasser: Benjamin Schwimmer, Henderson, Norman D., Olson, B. H.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - therapy
Antibiotics
Cultural groups
Gonorrhea
Gonorrhea - therapy
Medical treatment failures
Nursing homes
Old Medline
Penicillin
Penicillins
Public health
Reinfection
Sexually transmitted diseases
Syphilis
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Zusammenfassung:There is need for a new injectable antibiotic in the treatment of gonorrhea because of the rising problem of allergy to penicillin. Synnematin B, a new antibiotic, has been demonstrated to be effective in vitro against Neisseria gonorrhoeae. A single injection of 300,000 units of synnematin B was employed in the treatment of each of 132 male patients with acute gonorrhea. No serious side effects or allergic reactions resulted. A 4 percent failure rate was observed. Further study of the use of synnematin B in the treatment of gonorrhea is indicated.
ISSN:0094-6214
DOI:10.2307/4591225