Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2007-07, Vol.51 (7), p.2351-2358
Hauptverfasser:	STONE, Nimalie D, DUNAWAY, Shelia B, PARK, Jeong-Gun, LALAMA, Christina, SNYDER, Sally, KALLUNGAL, Beatrice, KLINGMAN, Karin L, HENDRIX, Craig W, FLEXNER, Charles, TIERNEY, Camlin, CALANDRA, Gary B, BECKER, Stephen, CAO, Ying-Jun, WIGGINS, Ilene P, CONLEY, Jeanne, MACFARLAND, Ron T
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Area Under Curve Biological and medical sciences Cohort Studies Dose-Response Relationship, Drug Fasting Half-Life Headache - chemically induced Heterocyclic Compounds, 1-Ring Heterocyclic Compounds, 1-Ring - administration & dosage Heterocyclic Compounds, 1-Ring - adverse effects Heterocyclic Compounds, 1-Ring - blood Heterocyclic Compounds, 1-Ring - pharmacokinetics Heterocyclic Compounds, 1-Ring - urine Human immunodeficiency virus 1 Humans Leukocytes - drug effects Male Medical sciences Middle Aged Pharmacology. Drug treatments Receptors, CXCR4 Receptors, CXCR4 - antagonists & inhibitors Time Factors
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Zusammenfassung:	ERRATUM ( vol. 51 , p. 3047 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.00013-07