High serum level of soluble CD30 in acute primary HIV‐1 infection

CD30 has been suggested to play a role in HIV infection. In this study the serum concentration of soluble CD30 (sCD30) was determined by an ELISA essay on samples collected from patients with acute primary HIV‐1 infection during the acute phase (n = 17) and after seroconversion (n = 13). sCD30 durin...

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Veröffentlicht in:	Clinical and experimental immunology 1997-05, Vol.108 (2), p.251-253
Hauptverfasser:	PIZZOLO, G., VINANTE, F., NADALI, G., KRAMPERA, M., MOROSATO, L., CHILOSI, M., RAITERI, R., SINICCO, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute HIV‐1 infection Adult AIDS/HIV Biological and medical sciences CD30 Female HIV Antigens - blood HIV Infections - blood HIV Infections - immunology HIV Infections - virology HIV-1 - immunology human immunodeficiency virus 1 Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Ki-1 Antigen - blood Male Medical sciences Middle Aged Original Solubility soluble CD30
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Zusammenfassung:	CD30 has been suggested to play a role in HIV infection. In this study the serum concentration of soluble CD30 (sCD30) was determined by an ELISA essay on samples collected from patients with acute primary HIV‐1 infection during the acute phase (n = 17) and after seroconversion (n = 13). sCD30 during acute infection was consistently elevated (137.58 ± 120.33 versus 6.4 ± 5.4 U/ml (mean ± s.d.) in normal controls; P
ISSN:	0009-9104 1365-2249
DOI:	10.1046/j.1365-2249.1997.d01-1005.x