Purpura associated with hypergammaglobulinemia, renal tubular acidosis and osteomalacia
Two patients with hyperglobulinemia associated with purpura were studied. One had features of Sjögren's syndrome, while the other appeared to have a primary condition -- "chronic benign purpura". Both patients also had renal tubular acidosis, osteomalacia and renal calculi, with distu...
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| Veröffentlicht in: | Canadian Medical Association journal 1977-01, Vol.116 (1), p.53-58 |
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| creator | Marquez-Julio, A Rapoport, A Wilansky, D. L Rabinovich, S Chamberlain, D |
| description | Two patients with hyperglobulinemia associated with purpura were studied. One had features of Sjögren's syndrome, while the other appeared to have a primary condition -- "chronic benign purpura". Both patients also had renal tubular acidosis, osteomalacia and renal calculi, with disturbed calcium metabolism and acid-base balance. Autoantibodies were detected in the serum of both patients, and mononuclear cell infiltrates were noted in skin and kidney biopsies from both. |
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L ; Rabinovich, S ; Chamberlain, D</creator><creatorcontrib>Marquez-Julio, A ; Rapoport, A ; Wilansky, D. L ; Rabinovich, S ; Chamberlain, D</creatorcontrib><description>Two patients with hyperglobulinemia associated with purpura were studied. One had features of Sjögren's syndrome, while the other appeared to have a primary condition -- "chronic benign purpura". Both patients also had renal tubular acidosis, osteomalacia and renal calculi, with disturbed calcium metabolism and acid-base balance. Autoantibodies were detected in the serum of both patients, and mononuclear cell infiltrates were noted in skin and kidney biopsies from both.</description><identifier>ISSN: 0008-4409</identifier><identifier>PMID: 832220</identifier><language>eng</language><publisher>Canada: Can Med Assoc</publisher><subject>Acid-Base Equilibrium ; Acidosis, Renal Tubular - complications ; Acidosis, Renal Tubular - diagnosis ; Blood Proteins - analysis ; Electrolytes - blood ; Female ; Humans ; Ilium - pathology ; Immunoglobulins - analysis ; Kidney - pathology ; Kidney Function Tests ; Middle Aged ; Osteomalacia - complications ; Osteomalacia - diagnosis ; Purpura, Hyperglobulinemic - complications ; Purpura, Hyperglobulinemic - diagnosis ; Sjogren's Syndrome - complications ; Sjogren's Syndrome - diagnosis ; Skin - pathology</subject><ispartof>Canadian Medical Association journal, 1977-01, Vol.116 (1), p.53-58</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1879134/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1879134/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/832220$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Marquez-Julio, A</creatorcontrib><creatorcontrib>Rapoport, A</creatorcontrib><creatorcontrib>Wilansky, D. L</creatorcontrib><creatorcontrib>Rabinovich, S</creatorcontrib><creatorcontrib>Chamberlain, D</creatorcontrib><title>Purpura associated with hypergammaglobulinemia, renal tubular acidosis and osteomalacia</title><title>Canadian Medical Association journal</title><addtitle>Can Med Assoc J</addtitle><description>Two patients with hyperglobulinemia associated with purpura were studied. One had features of Sjögren's syndrome, while the other appeared to have a primary condition -- "chronic benign purpura". Both patients also had renal tubular acidosis, osteomalacia and renal calculi, with disturbed calcium metabolism and acid-base balance. Autoantibodies were detected in the serum of both patients, and mononuclear cell infiltrates were noted in skin and kidney biopsies from both.</description><subject>Acid-Base Equilibrium</subject><subject>Acidosis, Renal Tubular - complications</subject><subject>Acidosis, Renal Tubular - diagnosis</subject><subject>Blood Proteins - analysis</subject><subject>Electrolytes - blood</subject><subject>Female</subject><subject>Humans</subject><subject>Ilium - pathology</subject><subject>Immunoglobulins - analysis</subject><subject>Kidney - pathology</subject><subject>Kidney Function Tests</subject><subject>Middle Aged</subject><subject>Osteomalacia - complications</subject><subject>Osteomalacia - diagnosis</subject><subject>Purpura, Hyperglobulinemic - complications</subject><subject>Purpura, Hyperglobulinemic - diagnosis</subject><subject>Sjogren's Syndrome - complications</subject><subject>Sjogren's Syndrome - diagnosis</subject><subject>Skin - pathology</subject><issn>0008-4409</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkEtLxDAUhbvwNY7-Axfd6MpCHk2bbAQZfMGALhSX4bZJ20ja1KS1zL83MCK6unC-wzmXc5CsEEI8y3MkTpLTED4QIpSg_Dg54pQQglbJ-8vsx9lDCiG42sCkVbqYqUu73ah9C30PrXXVbM2gewPXqdcD2HSaowQ-hdooF0xIYVCpC5N2Pdgowlly2IAN-vznrpO3-7vXzWO2fX542txus44INGWYAfCqYUjhqlCsojw-yxjTdSloxSgHldOG16wQWKhSQ46UaJqqoEA5xoquk5t97jhXvVa1HiYPVo7e9OB30oGR_8lgOtm6L4l5KTDNY8DVT4B3n7MOk-xNqLW1MGg3B8lpKYQgJBov_jb9VuyXjPhyjzvTdovxWoY4hY1mLJdlwbiQWDJKvwHaan6P</recordid><startdate>19770108</startdate><enddate>19770108</enddate><creator>Marquez-Julio, A</creator><creator>Rapoport, A</creator><creator>Wilansky, D. L</creator><creator>Rabinovich, S</creator><creator>Chamberlain, D</creator><general>Can Med Assoc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19770108</creationdate><title>Purpura associated with hypergammaglobulinemia, renal tubular acidosis and osteomalacia</title><author>Marquez-Julio, A ; Rapoport, A ; Wilansky, D. L ; Rabinovich, S ; Chamberlain, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h290t-15aa8bf50d1b6d5b38440555ec793b538ad43f8c56919d7ea40d9ffb63a3811d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Acid-Base Equilibrium</topic><topic>Acidosis, Renal Tubular - complications</topic><topic>Acidosis, Renal Tubular - diagnosis</topic><topic>Blood Proteins - analysis</topic><topic>Electrolytes - blood</topic><topic>Female</topic><topic>Humans</topic><topic>Ilium - pathology</topic><topic>Immunoglobulins - analysis</topic><topic>Kidney - pathology</topic><topic>Kidney Function Tests</topic><topic>Middle Aged</topic><topic>Osteomalacia - complications</topic><topic>Osteomalacia - diagnosis</topic><topic>Purpura, Hyperglobulinemic - complications</topic><topic>Purpura, Hyperglobulinemic - diagnosis</topic><topic>Sjogren's Syndrome - complications</topic><topic>Sjogren's Syndrome - diagnosis</topic><topic>Skin - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Marquez-Julio, A</creatorcontrib><creatorcontrib>Rapoport, A</creatorcontrib><creatorcontrib>Wilansky, D. L</creatorcontrib><creatorcontrib>Rabinovich, S</creatorcontrib><creatorcontrib>Chamberlain, D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Canadian Medical Association journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marquez-Julio, A</au><au>Rapoport, A</au><au>Wilansky, D. L</au><au>Rabinovich, S</au><au>Chamberlain, D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Purpura associated with hypergammaglobulinemia, renal tubular acidosis and osteomalacia</atitle><jtitle>Canadian Medical Association journal</jtitle><addtitle>Can Med Assoc J</addtitle><date>1977-01-08</date><risdate>1977</risdate><volume>116</volume><issue>1</issue><spage>53</spage><epage>58</epage><pages>53-58</pages><issn>0008-4409</issn><abstract>Two patients with hyperglobulinemia associated with purpura were studied. One had features of Sjögren's syndrome, while the other appeared to have a primary condition -- "chronic benign purpura". Both patients also had renal tubular acidosis, osteomalacia and renal calculi, with disturbed calcium metabolism and acid-base balance. Autoantibodies were detected in the serum of both patients, and mononuclear cell infiltrates were noted in skin and kidney biopsies from both.</abstract><cop>Canada</cop><pub>Can Med Assoc</pub><pmid>832220</pmid><tpages>6</tpages></addata></record> |
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| ispartof | Canadian Medical Association journal, 1977-01, Vol.116 (1), p.53-58 |
| issn | 0008-4409 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1879134 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Acid-Base Equilibrium Acidosis, Renal Tubular - complications Acidosis, Renal Tubular - diagnosis Blood Proteins - analysis Electrolytes - blood Female Humans Ilium - pathology Immunoglobulins - analysis Kidney - pathology Kidney Function Tests Middle Aged Osteomalacia - complications Osteomalacia - diagnosis Purpura, Hyperglobulinemic - complications Purpura, Hyperglobulinemic - diagnosis Sjogren's Syndrome - complications Sjogren's Syndrome - diagnosis Skin - pathology |
| title | Purpura associated with hypergammaglobulinemia, renal tubular acidosis and osteomalacia |
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