Acute myocardial infarction: the case for pre-hospital thrombolysis with or without percutaneous coronary intervention

[...]there has been a move towards the administration of thrombolytic treatment before hospital admission. In another observational study, 49% of patients receiving pre-hospital lysis had TIMI grade 3 flow which increased to 92% with PCI. 22 The ADMIRAL trial 23 showed a reduction in primary end poi...

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Veröffentlicht in:	Heart (British Cardiac Society) 2005-06, Vol.91 (suppl 3), p.iii7-iii11
1. Verfasser:	Schofield, P M
Format:	Artikel
Sprache:	eng
Schlagworte:	acute myocardial infarction Angioplasty, Balloon, Coronary - methods Coronary vessels Emergency Medical Services - methods Emergency Treatment EMIP European myocardial infarction project Fibrinolytic Agents - therapeutic use global utilization of streptokinase and t-PA for occluded coronary arteries GUSTO Heart attacks Humans Medical imaging MITI Mortality Myocardial Infarction - therapy myocardial infarction triage and intervention Pain Patients PCI percutaneous coronary intervention PRAGUE pre-hospital thrombolysis primary angioplasty vs immediate thrombolysis vs combined strategy for patients with acute myocardial infarction Randomized Controlled Trials as Topic Recombinant Proteins - therapeutic use Studies Thrombolytic Therapy - methods thrombolytic treatment Tissue Plasminogen Activator - therapeutic use Veins & arteries
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Beschreibung
Zusammenfassung:	[...]there has been a move towards the administration of thrombolytic treatment before hospital admission. In another observational study, 49% of patients receiving pre-hospital lysis had TIMI grade 3 flow which increased to 92% with PCI. 22 The ADMIRAL trial 23 showed a reduction in primary end point (death, reinfarction, and need for urgent revascularisation) in those patients treated with glycoprotein IIb/IIIa inhibitors (7.4%) as compared to placebo (15.9%) before PCI for acute myocardial infarction.
ISSN:	1355-6037 1468-201X
DOI:	10.1136/hrt.2004.058529