Endoscopic indications for endoscopic mucosal resection of laterally spreading tumours in the colorectum

Background: Laterally spreading tumours (LSTs) in the colorectum are usually removed by endoscopic mucosal resection (EMR) even when large in size. LSTs with deeper submucosal (sm) invasion, however, should not be treated by EMR because of the higher risk of lymph node metastasis. Aims: To determine...

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Veröffentlicht in:Gut 2006-11, Vol.55 (11), p.1592-1597
Hauptverfasser: Uraoka, T, Saito, Y, Matsuda, T, Ikehara, H, Gotoda, T, Saito, D, Fujii, T
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Sprache:eng
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Zusammenfassung:Background: Laterally spreading tumours (LSTs) in the colorectum are usually removed by endoscopic mucosal resection (EMR) even when large in size. LSTs with deeper submucosal (sm) invasion, however, should not be treated by EMR because of the higher risk of lymph node metastasis. Aims: To determine which endoscopic criteria, including high magnification pit pattern analysis, are associated with sm invasion in LSTs and clarify indications for EMR. Methods: Eight endoscopic criteria from 511 colorectal LSTs (granular type (LST-G type); non-granular type (LST-NG type)) were evaluated retrospectively for association with sm invasion, and compared with histopathological findings. Results: LST-NG type had a significantly higher frequency of sm invasion than LST-G type (14% v 7%; p
ISSN:0017-5749
1468-3288
DOI:10.1136/gut.2005.087452