Neoadjuvant chemoradiation treatment impairs accuracy of MRI staging in rectal carcinoma

Neoadjuvant chemoradiation treatment impairs accuracy of MRI staging in rectal carcinoma

High spatial resolution magnet resonance imaging (MRI) with intraluminary contrast and endorectal ultrasonography (EUS) (Olympus EU-M30S, 12 MHz) were performed before and after nCRT as part of their preoperative staging. Depth of extramural invasion, nodal involvement, and circumferential resection...

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Veröffentlicht in:Gut 2006-08, Vol.55 (8), p.1214-1215
Hauptverfasser: Jonas, J, Bähr, R
Format: Artikel
Sprache:eng
Schlagworte:
Accuracy
Adenocarcinoma - drug therapy
Adenocarcinoma - pathology
Adenocarcinoma - radiotherapy
Aged
Female
Humans
Letters
Magnetic Resonance Imaging
Male
Middle Aged
neoadjuvant chemoradiotherapy
Neoadjuvant Therapy
Neoplasm Staging
NMR
Nuclear magnetic resonance
Radiation therapy
rectal carcinoma
Rectal Neoplasms - drug therapy
Rectal Neoplasms - pathology
Rectal Neoplasms - radiotherapy
staging
Tumors
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Zusammenfassung:High spatial resolution magnet resonance imaging (MRI) with intraluminary contrast and endorectal ultrasonography (EUS) (Olympus EU-M30S, 12 MHz) were performed before and after nCRT as part of their preoperative staging. Depth of extramural invasion, nodal involvement, and circumferential resection margin involvement are prognostic markers in many studies. 1 Total mesorectal excision decreased local recurrence rates below 10%, 2 achieving further improvement by long course nCRT.
ISSN:0017-5749
1468-3288
DOI:10.1136/gut.2006.095034