Livedo Reticularis during Amantadine Treatment

Livedo reticularis is a common side effect of treatment with amantadine for Parkinson's disease. Investigation of 40 such patients suggests that the livedo is a physiological response provoked by depletion of catecholamine stores in peripheral nerve terminals.

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Bibliographische Detailangaben
Veröffentlicht in:	BMJ 1971-06, Vol.2 (5762), p.627-628
Hauptverfasser:	Vollum, Dorothy I., Parkes, J. D., Doyle, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amantadine - adverse effects Ankle Blood vessels Blood Vessels - drug effects Discoloration Edema Edema - complications Epinephrine - pharmacology Female Humans Isoproterenol - pharmacology Livedo reticularis Male Men Middle Aged Norepinephrine - pharmacology Pallor Papers and Originals Parkinson disease Parkinson Disease - drug therapy Pathology Posture Skin Skin - blood supply Skin Diseases - chemically induced Skin Diseases - complications
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Beschreibung
Zusammenfassung:	Livedo reticularis is a common side effect of treatment with amantadine for Parkinson's disease. Investigation of 40 such patients suggests that the livedo is a physiological response provoked by depletion of catecholamine stores in peripheral nerve terminals.
ISSN:	0007-1447 0959-8138 1468-5833
DOI:	10.1136/bmj.2.5762.627