Effect of Vagotomy on Ascorbic Acid Nutrition in Patients with Peptic Ulcer

In 33 patients undergoing surgery for peptic ulcer it was found that both the dietary and the leucocyte ascorbic acid levels fell below the accepted normal values. Although after vagotomy the dietary intake improved dramatically, this was accompanied by only a small rise in leucocyte ascorbic acid l...

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Veröffentlicht in:	BMJ 1972-06, Vol.2 (5816), p.738-740
Hauptverfasser:	MacDonald, J. A. E., Cohen, M. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Achlorhydria Adolescent Adult Aged Ascorbic Acid - blood Ascorbic Acid - physiology Diet Female Gastric Juice - metabolism Humans Insulin Insulin - pharmacology Leukocytes Leukocytes - analysis Male Medical journals Middle Aged Nutrition Nutrition Disorders - blood Nutritional status Papers and Originals Pentagastrin - pharmacology Peptic ulcer Peptic Ulcer - surgery Platelets Vagotomy
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Beschreibung
Zusammenfassung:	In 33 patients undergoing surgery for peptic ulcer it was found that both the dietary and the leucocyte ascorbic acid levels fell below the accepted normal values. Although after vagotomy the dietary intake improved dramatically, this was accompanied by only a small rise in leucocyte ascorbic acid levels. Evidence has been presented that the reduction in gastric acid output after vagotomy might be responsible for this paradox.
ISSN:	0007-1447 0959-8138 1468-5833
DOI:	10.1136/bmj.2.5816.738