UniPep--a database for human N-linked glycosites: a resource for biomarker discovery
There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted...
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| Veröffentlicht in: | Genome Biology (Online Edition) 2006-08, Vol.7 (8), p.R73-1341, Article R73 |
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| creator | Zhang, Hui Loriaux, Paul Eng, Jimmy Campbell, David Keller, Andrew Moss, Pat Bonneau, Richard Zhang, Ning Zhou, Yong Wollscheid, Bernd Cooke, Kelly Yi, Eugene C Lee, Hookeun Peskind, Elaine R Zhang, Jing Smith, Richard D Aebersold, Ruedi |
| description | There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep http://www.unipep.org--a database of human N-linked glycosites--as a resource for biomarker discovery. |
| doi_str_mv | 10.1186/gb-2006-7-8-r73 |
| format | Article |
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(PNNL), Richland, WA (United States)</creatorcontrib><title>UniPep--a database for human N-linked glycosites: a resource for biomarker discovery</title><title>Genome Biology (Online Edition)</title><addtitle>Genome Biol</addtitle><description>There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. 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(PNNL), Richland, WA (United States)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>UniPep--a database for human N-linked glycosites: a resource for biomarker discovery</atitle><jtitle>Genome Biology (Online Edition)</jtitle><addtitle>Genome Biol</addtitle><date>2006-08-10</date><risdate>2006</risdate><volume>7</volume><issue>8</issue><spage>R73</spage><epage>1341</epage><pages>R73-1341</pages><artnum>R73</artnum><issn>1474-760X</issn><issn>1465-6906</issn><eissn>1474-760X</eissn><eissn>1465-6914</eissn><abstract>There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. 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| identifier | ISSN: 1474-760X |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; SpringerLink Journals - AutoHoldings; Springer Nature OA Free Journals |
| subjects | 60 APPLIED LIFE SCIENCES Analysis BASIC BIOLOGICAL SCIENCES Biological markers biomarkers Blood proteins Computational Biology - methods Criminal investigation Databases, Genetic DISEASES Genetic Markers - genetics glycopeptides Glycopeptides - blood Glycopeptides - chemical synthesis Glycopeptides - genetics Humans Mass Spectrometry MASS SPECTROSCOPY PEPTIDES PLASMA protein secretion PROTEINS proteomics SCREENS Software |
| title | UniPep--a database for human N-linked glycosites: a resource for biomarker discovery |
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