UniPep--a database for human N-linked glycosites: a resource for biomarker discovery

There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted...

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Veröffentlicht in:Genome Biology (Online Edition) 2006-08, Vol.7 (8), p.R73-1341, Article R73
Hauptverfasser: Zhang, Hui, Loriaux, Paul, Eng, Jimmy, Campbell, David, Keller, Andrew, Moss, Pat, Bonneau, Richard, Zhang, Ning, Zhou, Yong, Wollscheid, Bernd, Cooke, Kelly, Yi, Eugene C, Lee, Hookeun, Peskind, Elaine R, Zhang, Jing, Smith, Richard D, Aebersold, Ruedi
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Sprache:eng
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Zusammenfassung:There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep http://www.unipep.org--a database of human N-linked glycosites--as a resource for biomarker discovery.
ISSN:1474-760X
1465-6906
1474-760X
1465-6914
DOI:10.1186/gb-2006-7-8-r73