Germline testing of mismatch repair genes is not aided by prescreening tumours for allelic loss

Germline testing of mismatch repair genes is not aided by prescreening tumours for allelic loss

Figure 1 Loss of heterozygosity analysis of four mismatch repair genes tumours from seven individuals with germline mutations in hMSH2.

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Bibliographische Detailangaben
Veröffentlicht in:Gut 2004-03, Vol.53 (3), p.471-472
Hauptverfasser: Ward, R L, Mokany, E
Format: Artikel
Sprache:eng
Schlagworte:
allelic loss
Base Pair Mismatch
cancer
Colorectal cancer
Colorectal Neoplasms, Hereditary Nonpolyposis - genetics
Genes
Genetic recombination
Germ-Line Mutation
Humans
Letter
Loss of Heterozygosity
mismatch repair genes
Mutation
Tumors
tumours
Yeast
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Beschreibung
Zusammenfassung:Figure 1 Loss of heterozygosity analysis of four mismatch repair genes tumours from seven individuals with germline mutations in hMSH2.
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.2003.031716