High molecular weight caldesmon positive stromal cells in the capsule of hepatocellular carcinomas

Aims: To investigate the smooth muscle nature of the stromal cells in the capsule of hepatocellular carcinomas. Methods: Immunohistochemical analysis using monoclonal antibody to high molecular weight caldesmon (HCD), a highly specific marker for smooth muscle cells, was performed in 33 encapsulated...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of clinical pathology 2004-07, Vol.57 (7), p.776-777
Hauptverfasser: Nakayama, H, Enzan, H, Yamamoto, M, Miyazaki, E, Yasui, W
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Aims: To investigate the smooth muscle nature of the stromal cells in the capsule of hepatocellular carcinomas. Methods: Immunohistochemical analysis using monoclonal antibody to high molecular weight caldesmon (HCD), a highly specific marker for smooth muscle cells, was performed in 33 encapsulated hepatocellular carcinomas and adjacent hepatic tissues. Results: HCD positive stromal cells were detected in the capsule of 21 of the 33 hepatocellular carcinomas examined. Conclusions: The capsule of hepatocellular carcinomas contains smooth muscle cells.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.2004.016279