Anosognosia and mania associated with right thalamic haemorrhage

Functional MRI 2 performed the same day demonstrated a 2 cm area of absent cerebral blood volume at the posterior margin of the right thalamus without any evidence of decreased cerebral blood volume within the right parietal, frontal, or temporal cortex. Weinstein and Kahn 5 noted that euphoria was common in patients with anosognosia. [...]although Cutting 6 emphasised that apathy is the mood more usually associated with anosognosia, 10% of his patients with anosognosia were described as having "euphoric mood." [...]Starksteinet al, 7 finding that similar frequencies and severities of major and minor depression were present in patients with and without anosognosia, suggest that a particular mood state may not necessarily influence insight.