Antimicrobial treatment for Chlamydia induced reactive arthritis

The antibiotics studied previously included tetracyclines, ciprofloxacin, and now azithromycin. 1, 5, 6 Chlamydia has demonstrated in vitro resistance to all of these antibiotics upon chronic administration. 7, 8 Further, ciprofloxacin has been shown to cause tendon based inflammation by potentiatin...

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Veröffentlicht in:	Annals of the rheumatic diseases 2005-03, Vol.64 (3), p.512-3; author reply 513
Hauptverfasser:	Carter, J D, Valeriano, J, Vasey, F B
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Antibiotics Antimicrobial agents Arthritis Arthritis, Reactive - drug therapy azithromycin Azithromycin - therapeutic use Chlamydia Chlamydia Infections - drug therapy doxycycline Humans Infections Matters Arising Organisms reactive arthritis rifampin Sexually transmitted diseases STD Treatment Outcome
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Zusammenfassung:	The antibiotics studied previously included tetracyclines, ciprofloxacin, and now azithromycin. 1, 5, 6 Chlamydia has demonstrated in vitro resistance to all of these antibiotics upon chronic administration. 7, 8 Further, ciprofloxacin has been shown to cause tendon based inflammation by potentiating interleukin 1Î² stimulated metalloproteinase-3 output in tendons. 9 Is this then the proper antibiotic to choose in the treatment of an enthesophyte based inflammatory arthritis?
ISSN:	0003-4967 1468-2060