Angiotensin converting enzyme (ACE) gene polymorphisms and lupus disease severity: a promising link

Informed consent was taken from all participants and international guidelines for sample collection were followed. 6 All patients fulfilled the American College of Rheumatology criteria for SLE. 7 We used the Systemic Lupus Activity Measure (SLAM) 8 score at diagnosis as an indicator of disease seve...

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Veröffentlicht in:	Annals of the rheumatic diseases 2005-01, Vol.64 (1), p.164-165
Hauptverfasser:	Saeed, M, Mekan, S F, Rabbani, M A, Arain, F M, Arif, M, Shaharyar, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult angiotensin converting enzyme Asian subjects Biological and medical sciences Case-Control Studies Confidence intervals Dermatology Female Genes Genetic Predisposition to Disease Haplotypes Humans Letter Lupus Lupus Erythematosus, Systemic - enzymology Lupus Erythematosus, Systemic - genetics Male Medical sciences Middle Aged Peptidyl-Dipeptidase A - genetics polymerase chain reaction Polymorphism, Genetic polymorphisms Skin involvement in other diseases. Miscellaneous. General aspects systemic lupus erythematosus
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Zusammenfassung:	Informed consent was taken from all participants and international guidelines for sample collection were followed. 6 All patients fulfilled the American College of Rheumatology criteria for SLE. 7 We used the Systemic Lupus Activity Measure (SLAM) 8 score at diagnosis as an indicator of disease severity; a SLAM score [= or >, slanted]20 indicating severe SLE and [= or
ISSN:	0003-4967 1468-2060
DOI:	10.1136/ard.2004.020834