Massive pleural effusion and marked increase of CA-125

The tumour associated CA-125 antigen is widely used in monitoring ovarian carcinoma. In women with a massive pleural effusion and ascites, markedly increased CA-125 levels may lead to an erroneous diagnosis of ovarian cancer. Very high levels of tumour markers may be present in patients with benign...

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Veröffentlicht in:	Postgraduate medical journal 2004-05, Vol.80 (943), p.300-301
Hauptverfasser:	Hussain, S F, Grayez, J, Grigorian, A, Green, J T
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Adult Alcohol Anti-Bacterial Agents - therapeutic use Antibiotics Antigens ascites Biological and medical sciences Biomarkers Breast cancer CA-125 CA-125 Antigen - blood Case Report Cellular biology chronic liver disease Diagnosis, Differential Diuretics Diuretics - therapeutic use Drainage Dyspnea - etiology Dyspnea - therapy Fatal Outcome Female General aspects Humans Intensive care Liver cirrhosis Liver diseases Medical sciences Metastasis Ovarian cancer Patients pleural effusion Pleural Effusion - blood Pleural Effusion - etiology Pneumology Respiration, Artificial Respiratory system : syndromes and miscellaneous diseases Tomography Tuberculosis Ultrasonic imaging
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description	The tumour associated CA-125 antigen is widely used in monitoring ovarian carcinoma. In women with a massive pleural effusion and ascites, markedly increased CA-125 levels may lead to an erroneous diagnosis of ovarian cancer. Very high levels of tumour markers may be present in patients with benign pleural effusion, ascites, and chronic liver disease. Raised levels of tumour markers in serum or pleural fluid, in the absence of positive cytology, should be interpreted with caution.
doi_str_mv	10.1136/pgmj.2003.012377
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Raised levels of tumour markers in serum or pleural fluid, in the absence of positive cytology, should be interpreted with caution.</description><identifier>ISSN: 0032-5473</identifier><identifier>EISSN: 1469-0756</identifier><identifier>DOI: 10.1136/pgmj.2003.012377</identifier><identifier>PMID: 15138325</identifier><language>eng</language><publisher>London: The Fellowship of Postgraduate Medicine</publisher><subject>Abdomen ; Adult ; Alcohol ; Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Antigens ; ascites ; Biological and medical sciences ; Biomarkers ; Breast cancer ; CA-125 ; CA-125 Antigen - blood ; Case Report ; Cellular biology ; chronic liver disease ; Diagnosis, Differential ; Diuretics ; Diuretics - therapeutic use ; Drainage ; Dyspnea - etiology ; Dyspnea - therapy ; Fatal Outcome ; Female ; General aspects ; Humans ; Intensive care ; Liver cirrhosis ; Liver diseases ; Medical sciences ; Metastasis ; Ovarian cancer ; Patients ; pleural effusion ; Pleural Effusion - blood ; Pleural Effusion - etiology ; Pneumology ; Respiration, Artificial ; Respiratory system : syndromes and miscellaneous diseases ; Tomography ; Tuberculosis ; Ultrasonic imaging</subject><ispartof>Postgraduate medical journal, 2004-05, Vol.80 (943), p.300-301</ispartof><rights>Copyright 2004 The Fellowship of Postgraduate Medicine</rights><rights>2004 INIST-CNRS</rights><rights>Copyright: 2004 Copyright 2004 The Fellowship of Postgraduate Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b456t-1ab400b78e717ada31758ae6910f71b574aa4cce96d40b03d60ea5b1e29a607a3</citedby><cites>FETCH-LOGICAL-b456t-1ab400b78e717ada31758ae6910f71b574aa4cce96d40b03d60ea5b1e29a607a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1743006/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1743006/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15849038$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15138325$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hussain, S F</creatorcontrib><creatorcontrib>Grayez, J</creatorcontrib><creatorcontrib>Grigorian, A</creatorcontrib><creatorcontrib>Green, J T</creatorcontrib><title>Massive pleural effusion and marked increase of CA-125</title><title>Postgraduate medical journal</title><addtitle>Postgrad Med J</addtitle><description>The tumour associated CA-125 antigen is widely used in monitoring ovarian carcinoma. In women with a massive pleural effusion and ascites, markedly increased CA-125 levels may lead to an erroneous diagnosis of ovarian cancer. Very high levels of tumour markers may be present in patients with benign pleural effusion, ascites, and chronic liver disease. Raised levels of tumour markers in serum or pleural fluid, in the absence of positive cytology, should be interpreted with caution.</description><subject>Abdomen</subject><subject>Adult</subject><subject>Alcohol</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Antigens</subject><subject>ascites</subject><subject>Biological and medical sciences</subject><subject>Biomarkers</subject><subject>Breast cancer</subject><subject>CA-125</subject><subject>CA-125 Antigen - blood</subject><subject>Case Report</subject><subject>Cellular biology</subject><subject>chronic liver disease</subject><subject>Diagnosis, Differential</subject><subject>Diuretics</subject><subject>Diuretics - therapeutic use</subject><subject>Drainage</subject><subject>Dyspnea - etiology</subject><subject>Dyspnea - therapy</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Intensive care</subject><subject>Liver cirrhosis</subject><subject>Liver diseases</subject><subject>Medical sciences</subject><subject>Metastasis</subject><subject>Ovarian cancer</subject><subject>Patients</subject><subject>pleural effusion</subject><subject>Pleural Effusion - blood</subject><subject>Pleural Effusion - etiology</subject><subject>Pneumology</subject><subject>Respiration, Artificial</subject><subject>Respiratory system : syndromes and miscellaneous diseases</subject><subject>Tomography</subject><subject>Tuberculosis</subject><subject>Ultrasonic imaging</subject><issn>0032-5473</issn><issn>1469-0756</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkU1v00AQhleIiobAnROyhOCCHGa8X_YFqYqgpQpwgai31dgelw2OHbxx1f57NnJUChdOc5hnXj2jV4gXCAtEad7trrebRQYgF4CZtPaRmKEyRQpWm8diFhdZqpWVp-JpCBsAlFbhE3GKGmUuMz0T5jOF4G842bU8DtQm3DRj8H2XUFcnWxp-cp34rhqYAid9kyzPUsz0M3HSUBv4-XHOxfePH74tL9LV1_NPy7NVWipt9ilSqQBKm7NFSzVJtDonNgVCY7HUVhGpquLC1ApKkLUBJl0iZwUZsCTn4v2UuxvLLdcVd_so6XaDj2p3rifv_t50_oe77m8cWiUBTAx4cwwY-l8jh73b-lBx21LH_RicxSKD3GIEX_0Dbvpx6OJzMStHXYCxMlIwUdXQhzBwc6-C4A6VuEMl7lCJmyqJJy8fvvDn4NhBBF4fAQoVtc1AXeXDAy5XBUR0LtKJ82HPt_f7WJGLala7L-ulW19cZZfr8yu3ivzbiS-j0X81fwNpOK_P</recordid><startdate>20040501</startdate><enddate>20040501</enddate><creator>Hussain, S F</creator><creator>Grayez, J</creator><creator>Grigorian, A</creator><creator>Green, J T</creator><general>The Fellowship of Postgraduate Medicine</general><general>BMJ</general><general>Oxford University Press</general><general>BMJ Group</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20040501</creationdate><title>Massive pleural effusion and marked increase of CA-125</title><author>Hussain, S F ; 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In women with a massive pleural effusion and ascites, markedly increased CA-125 levels may lead to an erroneous diagnosis of ovarian cancer. Very high levels of tumour markers may be present in patients with benign pleural effusion, ascites, and chronic liver disease. Raised levels of tumour markers in serum or pleural fluid, in the absence of positive cytology, should be interpreted with caution.</abstract><cop>London</cop><pub>The Fellowship of Postgraduate Medicine</pub><pmid>15138325</pmid><doi>10.1136/pgmj.2003.012377</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record>
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subjects	Abdomen Adult Alcohol Anti-Bacterial Agents - therapeutic use Antibiotics Antigens ascites Biological and medical sciences Biomarkers Breast cancer CA-125 CA-125 Antigen - blood Case Report Cellular biology chronic liver disease Diagnosis, Differential Diuretics Diuretics - therapeutic use Drainage Dyspnea - etiology Dyspnea - therapy Fatal Outcome Female General aspects Humans Intensive care Liver cirrhosis Liver diseases Medical sciences Metastasis Ovarian cancer Patients pleural effusion Pleural Effusion - blood Pleural Effusion - etiology Pneumology Respiration, Artificial Respiratory system : syndromes and miscellaneous diseases Tomography Tuberculosis Ultrasonic imaging
title	Massive pleural effusion and marked increase of CA-125
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