Serous effusions: diagnosis of malignancy beyond cytomorphology. An analytic review

In this brief review, the role of various ancillary techniques to detect malignancy in effusion fluid are evaluated and discussed. The data were collected from a large number of research articles published in various medical journals. The role of these techniques to increase the diagnostic accuracy...

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Veröffentlicht in:	Postgraduate medical journal 2003-10, Vol.79 (936), p.569-574
Hauptverfasser:	Mohanty, S K, Dey, P
Format:	Artikel
Sprache:	eng
Schlagworte:	AgNOR Analysis ancillary techniques Antigens argyrophilic nucleolar organiser regions Biological and medical sciences Biomarkers Biomarkers, Tumor - analysis Blood Group Antigens - analysis Blood groups Cancer Cell cycle Chromosomes cytology Deoxyribonucleic acid Diagnosis DNA EGP-2 epithelial glycoprotein-2 Exudates and transudates Flow Cytometry Fluids Fluorescent Antibody Technique Growth Substances - analysis HLA Antigens - analysis Host-tumor relations. Immunology. Biological markers Humans Image Interpretation, Computer-Assisted In Situ Hybridization Keratin Laboratories matrix metalloproteinases Medical sciences Mesothelioma Metastasis Methods Microscopy Microscopy, Electron MMP Molecular weight NOR nucleolar organiser regions Nucleolus Organizer Region - chemistry PCR Physiological aspects Pleural Effusion, Malignant - diagnosis polymerase chain reaction Polymerase Chain Reaction - methods reverse transcriptase Review serous effusion Serous membrane Telomerase Telomerase - metabolism Tumor Suppressor Protein p53 - metabolism Tumors vascular endothelial growth factor VEGF
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Beschreibung
Zusammenfassung:	In this brief review, the role of various ancillary techniques to detect malignancy in effusion fluid are evaluated and discussed. The data were collected from a large number of research articles published in various medical journals. The role of these techniques to increase the diagnostic accuracy in serous effusions is emphasised.
ISSN:	0032-5473 1469-0756
DOI:	10.1136/pmj.79.936.569