A common ancestor for COCH related cochleovestibular (DFNA9) patients in Belgium and The Netherlands bearing the P51S mutation
[...]it is commonly known that many hearing impaired people also suffer from balance problems. [...]it is now recognised that many syndromes with genetic hearing impairment also show a dysfunction of the vestibular system. 3 The prevalence of vestibular dysfunction may be severely underestimated, as...
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Veröffentlicht in: | Journal of medical genetics 2001-01, Vol.38 (1), p.61-64 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | [...]it is commonly known that many hearing impaired people also suffer from balance problems. [...]it is now recognised that many syndromes with genetic hearing impairment also show a dysfunction of the vestibular system. 3 The prevalence of vestibular dysfunction may be severely underestimated, as it often remains unnoticed until specialised vestibular tests are performed. [...]the data obtained here indicate that the Généthon genetic map around the COCHlocus is not reliable. [...]the intermarker distances around theCOCH gene are unknown and even a rough estimate of the age of the mutation is not feasible. |
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ISSN: | 0022-2593 1468-6244 |
DOI: | 10.1136/jmg.38.1.61 |