Why is there discordance between calcific aortic stenosis and coronary artery disease?

In the population based cardiovascular health study, the presence of aortic sclerosis on echocardiography in adults over age 65 years, with no known coronary artery disease at study entry, was associated with a 50% increased risk of cardiovascular mortality and myocardial infarction over a mean follow up interval of 5.5 years. 8 Although further studies are needed both to replicate this finding and to establish the mechanism of this association, it is unlikely that aortic sclerosis directly leads to adverse cardiovascular outcomes. [...]it should be noted that it is still a matter of debate not only how the VDR B/b polymorphism might influence bone density, but alsowhether this polymorphism truly affects bone density. [...]the apparent association between the VDR B allele and calcific aortic valve disease must be confirmed in additional studies before firm conclusions can be drawn about its role in this process.