Comparison of peripheral endothelial dysfunction and intimal media thickness in patients with suspected coronary artery disease

Objective Flow associated dilatation (FAD%) and intimal media thickness are established markers of early atherosclerosis. This study aimed to compare the ability of the non-invasive measurements FAD% and intimal media thickness to predict coronary artery disease. Methods FAD% and intimal media thick...

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Veröffentlicht in:	Heart (British Cardiac Society) 1998-10, Vol.80 (4), p.349-354
Hauptverfasser:	Enderle, M-D, Schroeder, S, Ossen, R, Meisner, C, Baumbach, A, Haering, H U, Karsch, K R, Pfohl, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Atherosclerosis Biological and medical sciences Brachial Artery - diagnostic imaging Cardiovascular disease Cardiovascular system Carotid arteries Carotid Artery, Common - diagnostic imaging Cholesterol Coronary Angiography coronary artery disease Coronary Disease - diagnostic imaging Coronary Disease - pathology Coronary Disease - physiopathology Coronary vessels Diabetes Diuretics Electrocardiography endothelial dysfunction Endothelium Endothelium, Vascular - diagnostic imaging Endothelium, Vascular - physiopathology Enzymes Female flow associated dilatation Glucose Heart attacks Humans Hypertension intimal media thickness Investigative techniques, diagnostic techniques (general aspects) Male Medical imaging Medical sciences Middle Aged Morphology Mortality Plasma Predictive Value of Tests Prospective Studies Reproducibility of Results Smoking Smooth muscle Substance abuse treatment Triglycerides Tunica Intima - pathology Ultrasonic imaging Ultrasonic investigative techniques Ultrasonography Vasodilation
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Beschreibung
Zusammenfassung:	Objective Flow associated dilatation (FAD%) and intimal media thickness are established markers of early atherosclerosis. This study aimed to compare the ability of the non-invasive measurements FAD% and intimal media thickness to predict coronary artery disease. Methods FAD% and intimal media thickness were determined using high resolution ultrasound in 122 patients with clinically suspected coronary artery disease before coronary angiography. Results are given as mean (SD). Results Patients with coronary artery disease had reduced FAD% compared with those with angiographically normal coronary vessels (3.7 (4.1) v 7.0 (3.5)%, p
ISSN:	1355-6037 1468-201X
DOI:	10.1136/hrt.80.4.349