Retroperitoneal haematoma after paracetamol increased anticoagulation

Drugs containing paracetamol are widely used as analgesics but may result in increased anticoagulation in patients who take warfarin, the mechanism being unclear. Retroperitoneal haemorrhage is a serious and well described complication in patients who develop increased anticoagulation; this may resu...

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Veröffentlicht in:	Emergency medicine journal : EMJ 2002-01, Vol.19 (1), p.84-85
1. Verfasser:	Andrews, F J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Acetaminophen - adverse effects Analgesics Analgesics, Non-Narcotic - adverse effects Anticoagulants Anticoagulants (Medicine) Arthritis Case Report Case studies Complications and side effects Drug interactions Drug Synergism Female femoral neuropathy Femoral Neuropathy - etiology Hematoma Hematoma - chemically induced Humans INR international normalised ratio International Normalized Ratio Middle Aged Pain paracetamol Patients retroperitoneal haematoma Retroperitoneal Space Ultrasonic imaging warfarin Warfarin - adverse effects Warfarin - therapeutic use
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Beschreibung
Zusammenfassung:	Drugs containing paracetamol are widely used as analgesics but may result in increased anticoagulation in patients who take warfarin, the mechanism being unclear. Retroperitoneal haemorrhage is a serious and well described complication in patients who develop increased anticoagulation; this may result in a femoral neuropathy. Both conservative and surgical treatments have been advocated for this complication.
ISSN:	1472-0205 1472-0213
DOI:	10.1136/emj.19.1.84