Therapy of subhyaloidal haemorrhage by intravitreal application of rtPA and SF6 gas

The intravitreal injection of rtPA and SF6 gas has recently been reported by different authors to induce pneumatic displacement of subretinal haemorrhage in cases of age related macular degeneration. 2 3 A significant reduction of central scotoma size with this comparably minimally invasive procedure has been pointed out, especially considering the minor side effects compared with the potential complications after vitrectomy with subretinal surgery. The low risk profile of the procedure has been pointed out for its use in subretinal haemorrhage. 2 3 Retinal break formation after intravitreal gas injection is a well known complication. [...]before gas injection a thorough examination of the peripheral retina should be carried out to detect any pre-existing breaks or degenerations.