Exhaled nitric oxide in chronically ventilated preterm infants

Exhaled nitric oxide (eNO) levels were measured in eight ventilated infants, mean gestational age 25.8 (SD 1.7) weeks and postnatal age 55 (SD 39) days, before and after three days of dexamethasone treatment. The eNO levels fell from a mean of 6.5 (SD 3.4) to 4.2 (SD 2.6) parts per billion (p = 0.03...

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Veröffentlicht in:	Archives of disease in childhood. Fetal and neonatal edition 2004-01, Vol.89 (1), p.F88-89
Hauptverfasser:	Williams, O, Bhat, R Y, Cheeseman, P, Rafferty, G F, Hannam, S, Greenough, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Inflammatory Agents - therapeutic use Artificial respiration Babies BAL bronchoalveolar lavage Carbon dioxide Carbon Dioxide - physiology Care and treatment Case Report Chronic Disease chronic lung disease CLD Cytokines Dexamethasone - therapeutic use Diseases eNO exhaled nitric oxide Gases Humans inducible nitric oxide synthetase Infant, Newborn Infant, Premature, Diseases - physiopathology Infants Infants (Premature) iNOS Lung Diseases - physiopathology Measurement Methods Nitric oxide Nitric Oxide - physiology Oxygen - physiology parts per billion Pediatric respiratory diseases Physiological aspects ppb prematurity Pulmonary function tests Respiration, Artificial - methods Respiratory distress syndrome Respiratory therapy Ventilation Ventilators
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Zusammenfassung:	Exhaled nitric oxide (eNO) levels were measured in eight ventilated infants, mean gestational age 25.8 (SD 1.7) weeks and postnatal age 55 (SD 39) days, before and after three days of dexamethasone treatment. The eNO levels fell from a mean of 6.5 (SD 3.4) to 4.2 (SD 2.6) parts per billion (p = 0.031) and the mean supplementary oxygen levels from 62% to 45% (p = 0.0078).
ISSN:	1359-2998 1468-2052
DOI:	10.1136/fn.89.1.F88