The significance of elevated CSF lactate

The final diagnosis of 158 patients who had a cerebrospinal fluid (CSF) lactate concentration greater than 2 mmol/l was ascertained. The conditions included seizures, inflammatory changes, and proven metabolic disorders. For the diagnosis of congenital lactic acidoses, CSF lactate should ideally be...

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Veröffentlicht in:	Archives of disease in childhood 2005-11, Vol.90 (11), p.1188-1189
Hauptverfasser:	Chow, S L, Rooney, Z J, Cleary, M A, Clayton, P T, Leonard, J V
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis, Lactic - cerebrospinal fluid Acidosis, Lactic - congenital Acidosis, Lactic - diagnosis Analysis Biological and medical sciences Biomarkers - cerebrospinal fluid cerebral inflammation cerebral ischaemia Cerebrospinal fluid Child Congenital diseases congenital lactic acidosis CSF Diagnosis Diagnosis, Differential Encephalitis General aspects Histology Hospitals Humans Illnesses Inborn errors of metabolism Inflammation - cerebrospinal fluid Inflammation - diagnosis Lactic Acid - cerebrospinal fluid Lactic acidosis Medical sciences Meningitis Metabolic diseases Metabolic disorders Metabolism, Inborn Errors - cerebrospinal fluid Metabolism, Inborn Errors - diagnosis Metabolism, Inborn errors of Miscellaneous mitochondrial disorder Neoplasms - cerebrospinal fluid Neoplasms - diagnosis Other metabolic disorders Patients Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Records (Forms) Referral Research and Development Seizures Seizures - cerebrospinal fluid Short Report
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Zusammenfassung:	The final diagnosis of 158 patients who had a cerebrospinal fluid (CSF) lactate concentration greater than 2 mmol/l was ascertained. The conditions included seizures, inflammatory changes, and proven metabolic disorders. For the diagnosis of congenital lactic acidoses, CSF lactate should ideally be measured in a seizure free patient after any acute illness.
ISSN:	0003-9888 1468-2044
DOI:	10.1136/adc.2005.075317