Using child reported respiratory symptoms to diagnose asthma in the community

Aims: To study how respiratory symptoms reported by children, with or without spirometry, could help to discriminate those with asthma from those without. Methods: Respiratory symptoms (frequent cough, frequent phlegm, and wheezing) reported by 1646 schoolchildren (aged 8–12 years) in a respiratory...

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Veröffentlicht in:	Archives of disease in childhood 2004-06, Vol.89 (6), p.544-548
Hauptverfasser:	Yu, I T S, Wong, T W, Li, W
Format:	Artikel
Sprache:	eng
Schlagworte:	Air pollution Asthma Asthma - diagnosis Asthma - physiopathology Biological and medical sciences Child Children Children & youth Chronic obstructive pulmonary disease, asthma Clinical Diagnosis confidence interval Diagnosis Diagnostic Tests Elementary Education Elementary Schools Female Females FEV forced expiratory volume Forced Expiratory Volume - physiology forced vital capacity FVC Gender Differences Girls Health aspects Humans likelihood ratio likelihood ratio for negative result likelihood ratio for positive result Male Males Medical sciences negative predictive value NLR NPV Original Outdoor air quality Parents Parents & parenting Physicians PLR Pneumology positive predictive value PPV predictive values Prevalence studies (Epidemiology) Probability Pulmonary manifestations of general diseases Questionnaires Reproducibility of Results Respiratory Sounds - diagnosis Respiratory Sounds - physiopathology Respiratory symptoms Self Disclosure Sensitivity and Specificity Statistical Significance Surveys and Questionnaires Vital Capacity - physiology
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Zusammenfassung:	Aims: To study how respiratory symptoms reported by children, with or without spirometry, could help to discriminate those with asthma from those without. Methods: Respiratory symptoms (frequent cough, frequent phlegm, and wheezing) reported by 1646 schoolchildren (aged 8–12 years) in a respiratory questionnaire and the FEV1:FVC ratio measured with spirometry (at three different cut-off values of 0.70, 0.75, and 0.80) were compared against the criterion standard of a physician diagnosis of asthma reported by the parents. Results: The overall prevalence of asthma was 6%; more boys had asthma. Wheezing had the best discriminating ability among the three symptoms and a cut-off point at 75% was best for the FEV1:FVC ratio. Combining wheezing with an FEV1:FVC ratio
ISSN:	0003-9888 1468-2044
DOI:	10.1136/adc.2003.033688