LHRH analogue and growth hormone did not improve the final height of a patient with juvenile hypothyroidism accompanied by precocious puberty

Minamitani et al reported that treatment with LHRH analogue and growth hormone in addition to thyroxine was successful in improving the final height and avoiding pubertal growth of patients with juvenile hypothyroidism in the prepubertal stage. 1 Difference between the report of Minamitaniet al and our case is that our patient already had the advanced bone age relative to height age and the progression of puberty at the start of treatment, to which our failure to improve the final height with the combination therapy might have been ascribed.