Primary manifestation of Henoch-Schönlein purpura during immunosuppressive treatment

Raised serum IgA concentration, circulating IgA immune complexes, IgA rheumatoid factor, an increased percentage of IgA bearing peripheral blood lymphocytes, etc, were demonstrated. 1 Triggering infectious mucosal stimuli are responsible for development of Henoch-Schönlein purpura and circulating dimeric IgA are distinctly involved in this process. 2 3 Whereas isolated cases of recurrent Henoch-Schönlein purpura nephritis in adults after renal transplantation have been observed, 4 this is to our knowledge the first report on a patient, who, despite of receiving regular immunosuppressive treatment after liver transplantation, developed a primary manifestation of Henoch-Schönlein purpura eight months later.