Low molecular weight heparins and hypoaldosteronism

Treatment with heparin can impair production of aldosterone, though this is usually not clinically important. We diagnosed hyperkalemia related to hypoaldosteronism in a 79 year old woman who was being treated with low molecular weight heparin; the condition resolved when the treatment was withdrawn...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BMJ 1990-06, Vol.300 (6737), p.1437-1438
Hauptverfasser:	Levesque, H, Verdier, S, Cailleux, N, Elie-Legrand, M C, Gancel, A, Basuyau, J P, Borg, J Y, Moore, N, Courtois, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aldosterone - blood Biological and medical sciences Biosynthesis Blood plasma Endocrinopathies Female Heparin Heparin, Low-Molecular-Weight - therapeutic use Humans hyperkalemia Hypoaldosteronism Hypoaldosteronism - blood Hypoaldosteronism - drug therapy Low molecular weights Male Medical sciences Medical specialists Middle Aged Potassium
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Treatment with heparin can impair production of aldosterone, though this is usually not clinically important. We diagnosed hyperkalemia related to hypoaldosteronism in a 79 year old woman who was being treated with low molecular weight heparin; the condition resolved when the treatment was withdrawn. This prompted a prospective, randomized systematic study of the effects of the low molecular weight heparins on adrenal function.
ISSN:	0959-8138 0959-8146 1468-5833 1756-1833
DOI:	10.1136/bmj.300.6737.1437