Appearance of Specific Colostrum Antibodies after Clinical Infection with Salmonella Typhimurium
Colostrum and serum antibodies to Salmonella typhimurium have been found in three patients after clinical gastrointestinal infection during pregnancy. High levels of colostrum IgA agglutinins were directed specifically against both the flagellar and somatic antigens of the infective organism. The le...
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| Veröffentlicht in: | BMJ 1974-08, Vol.3 (5926), p.307-309 |
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| container_issue | 5926 |
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| creator | Allardyce, R. A. Shearman, D. J. C. McClelland, D. B. L. Marwick, K. Simpson, A. J. Laidlaw, R. B. |
| description | Colostrum and serum antibodies to Salmonella typhimurium have been found in three patients after clinical gastrointestinal infection during pregnancy. High levels of colostrum IgA agglutinins were directed specifically against both the flagellar and somatic antigens of the infective organism. The levels of colostrum agglutinating activity exceeded those found in the patients sera, while control colostrum gave negative results. |
| doi_str_mv | 10.1136/bmj.3.5926.307 |
| format | Article |
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A. ; Shearman, D. J. C. ; McClelland, D. B. L. ; Marwick, K. ; Simpson, A. J. ; Laidlaw, R. B.</creator><creatorcontrib>Allardyce, R. A. ; Shearman, D. J. C. ; McClelland, D. B. L. ; Marwick, K. ; Simpson, A. J. ; Laidlaw, R. B.</creatorcontrib><description>Colostrum and serum antibodies to Salmonella typhimurium have been found in three patients after clinical gastrointestinal infection during pregnancy. High levels of colostrum IgA agglutinins were directed specifically against both the flagellar and somatic antigens of the infective organism. The levels of colostrum agglutinating activity exceeded those found in the patients sera, while control colostrum gave negative results.</description><identifier>ISSN: 0007-1447</identifier><identifier>ISSN: 0959-8138</identifier><identifier>EISSN: 1468-5833</identifier><identifier>DOI: 10.1136/bmj.3.5926.307</identifier><identifier>PMID: 4606237</identifier><language>eng</language><publisher>England: British Medical Journal Publishing Group</publisher><subject>Agglutination ; Agglutination Tests ; Agglutinins ; Antibodies ; Antibodies, Bacterial - analysis ; Antibody Formation ; Antigens ; Antigens, Bacterial - analysis ; Colostrum ; Colostrum - immunology ; Female ; Fluorescent Antibody Technique ; Gastrointestinal Diseases - immunology ; Humans ; Immunity, Maternally-Acquired ; Immunoglobulin A - analysis ; Immunoglobulins ; Immunology ; Infections ; Papers and Originals ; Pregnancy ; Pregnancy Complications, Infectious - immunology ; Salmonella ; Salmonella Infections - immunology ; Salmonella typhimurium ; Salmonella typhimurium - immunology</subject><ispartof>BMJ, 1974-08, Vol.3 (5926), p.307-309</ispartof><rights>Copyright 1974 British Medical Journal</rights><rights>Copyright BMJ Publishing Group LTD Aug 3, 1974</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b507t-f2ed1f9e6ed60b6e280a636f0b3cb7273c5220cb109efde4b1436a4f239d203a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/20469960$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/20469960$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,723,776,780,799,881,27901,27902,53766,53768,57992,58225</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4606237$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Allardyce, R. A.</creatorcontrib><creatorcontrib>Shearman, D. J. C.</creatorcontrib><creatorcontrib>McClelland, D. B. L.</creatorcontrib><creatorcontrib>Marwick, K.</creatorcontrib><creatorcontrib>Simpson, A. J.</creatorcontrib><creatorcontrib>Laidlaw, R. B.</creatorcontrib><title>Appearance of Specific Colostrum Antibodies after Clinical Infection with Salmonella Typhimurium</title><title>BMJ</title><addtitle>Br Med J</addtitle><description>Colostrum and serum antibodies to Salmonella typhimurium have been found in three patients after clinical gastrointestinal infection during pregnancy. High levels of colostrum IgA agglutinins were directed specifically against both the flagellar and somatic antigens of the infective organism. The levels of colostrum agglutinating activity exceeded those found in the patients sera, while control colostrum gave negative results.</description><subject>Agglutination</subject><subject>Agglutination Tests</subject><subject>Agglutinins</subject><subject>Antibodies</subject><subject>Antibodies, Bacterial - analysis</subject><subject>Antibody Formation</subject><subject>Antigens</subject><subject>Antigens, Bacterial - analysis</subject><subject>Colostrum</subject><subject>Colostrum - immunology</subject><subject>Female</subject><subject>Fluorescent Antibody Technique</subject><subject>Gastrointestinal Diseases - immunology</subject><subject>Humans</subject><subject>Immunity, Maternally-Acquired</subject><subject>Immunoglobulin A - analysis</subject><subject>Immunoglobulins</subject><subject>Immunology</subject><subject>Infections</subject><subject>Papers and Originals</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - immunology</subject><subject>Salmonella</subject><subject>Salmonella Infections - immunology</subject><subject>Salmonella typhimurium</subject><subject>Salmonella typhimurium - immunology</subject><issn>0007-1447</issn><issn>0959-8138</issn><issn>1468-5833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkc-L1DAcxYMo67Du1ZtQEAQPrfnVpL0IQ3V0YVVkVq8xTRMnY9t0k9Td_e9NmWH8cfEUvrxPHu_xAHiKYIEQYa_aYV-QoqwxKwjkD8AKUVblZUXIQ7CCEPIcUcofg4sQ9unEhFc1o2fgjDLI0rUC39bTpKWXo9KZM9l20soaq7LG9S5EPw_Zeoy2dZ3VIZMmap81vR2tkn12ORqtonVjdmvjLtvKfnCj7nuZXd9POzvM3s7DE_DIyD7oi-N7Dr5s3l437_OrT-8um_VV3paQx9xg3SFTa6Y7BlumcQUlI8zAlqiWY05UiTFULYK1Np2mLaKESWowqTsMiSTn4PXBd5rbQXdKj9HLXkzeDtLfCyet-FsZ7U58dz8FYghxzpLBi6OBdzezDlEMNqilzqjdHESFaV1SvIDP_wH3bvZjKicWIwRJWfFEFQdKeReC1-YUBUGxjCfSeIKIZTyRxksfnv1Z4IQfp_qt70N0_iRjSFldM5j0_KDbEPXdSZf-h2Cc8FJ8_NqIzZtts_n8oRYo8S8P_JLjP9l-Aek5vKc</recordid><startdate>19740803</startdate><enddate>19740803</enddate><creator>Allardyce, R. A.</creator><creator>Shearman, D. J. C.</creator><creator>McClelland, D. B. L.</creator><creator>Marwick, K.</creator><creator>Simpson, A. J.</creator><creator>Laidlaw, R. 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A. ; Shearman, D. J. C. ; McClelland, D. B. L. ; Marwick, K. ; Simpson, A. J. ; Laidlaw, R. 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A.</au><au>Shearman, D. J. C.</au><au>McClelland, D. B. L.</au><au>Marwick, K.</au><au>Simpson, A. J.</au><au>Laidlaw, R. B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Appearance of Specific Colostrum Antibodies after Clinical Infection with Salmonella Typhimurium</atitle><jtitle>BMJ</jtitle><addtitle>Br Med J</addtitle><date>1974-08-03</date><risdate>1974</risdate><volume>3</volume><issue>5926</issue><spage>307</spage><epage>309</epage><pages>307-309</pages><issn>0007-1447</issn><issn>0959-8138</issn><eissn>1468-5833</eissn><abstract>Colostrum and serum antibodies to Salmonella typhimurium have been found in three patients after clinical gastrointestinal infection during pregnancy. High levels of colostrum IgA agglutinins were directed specifically against both the flagellar and somatic antigens of the infective organism. The levels of colostrum agglutinating activity exceeded those found in the patients sera, while control colostrum gave negative results.</abstract><cop>England</cop><pub>British Medical Journal Publishing Group</pub><pmid>4606237</pmid><doi>10.1136/bmj.3.5926.307</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Agglutination Agglutination Tests Agglutinins Antibodies Antibodies, Bacterial - analysis Antibody Formation Antigens Antigens, Bacterial - analysis Colostrum Colostrum - immunology Female Fluorescent Antibody Technique Gastrointestinal Diseases - immunology Humans Immunity, Maternally-Acquired Immunoglobulin A - analysis Immunoglobulins Immunology Infections Papers and Originals Pregnancy Pregnancy Complications, Infectious - immunology Salmonella Salmonella Infections - immunology Salmonella typhimurium Salmonella typhimurium - immunology |
| title | Appearance of Specific Colostrum Antibodies after Clinical Infection with Salmonella Typhimurium |
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