Appearance of Specific Colostrum Antibodies after Clinical Infection with Salmonella Typhimurium

Colostrum and serum antibodies to Salmonella typhimurium have been found in three patients after clinical gastrointestinal infection during pregnancy. High levels of colostrum IgA agglutinins were directed specifically against both the flagellar and somatic antigens of the infective organism. The le...

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Veröffentlicht in:	BMJ 1974-08, Vol.3 (5926), p.307-309
Hauptverfasser:	Allardyce, R. A., Shearman, D. J. C., McClelland, D. B. L., Marwick, K., Simpson, A. J., Laidlaw, R. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglutination Agglutination Tests Agglutinins Antibodies Antibodies, Bacterial - analysis Antibody Formation Antigens Antigens, Bacterial - analysis Colostrum Colostrum - immunology Female Fluorescent Antibody Technique Gastrointestinal Diseases - immunology Humans Immunity, Maternally-Acquired Immunoglobulin A - analysis Immunoglobulins Immunology Infections Papers and Originals Pregnancy Pregnancy Complications, Infectious - immunology Salmonella Salmonella Infections - immunology Salmonella typhimurium Salmonella typhimurium - immunology
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Beschreibung
Zusammenfassung:	Colostrum and serum antibodies to Salmonella typhimurium have been found in three patients after clinical gastrointestinal infection during pregnancy. High levels of colostrum IgA agglutinins were directed specifically against both the flagellar and somatic antigens of the infective organism. The levels of colostrum agglutinating activity exceeded those found in the patients sera, while control colostrum gave negative results.
ISSN:	0007-1447 0959-8138 1468-5833
DOI:	10.1136/bmj.3.5926.307